Gene Symbol | GNGT1 |
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Entrez Gene | 2792 |
Alt Symbol | GNG1 |
Species | Human |
Gene Type | protein-coding |
Description | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 |
Other Description | guanine nucleotide-binding protein G(T) subunit gamma-T1|transducin gamma chain |
Swissprots | Q16026 O43835 A4D1H2 Q08447 Q6LCP6 P63211 |
Accessions | AAB92386 AAB92387 AAD13931 AAS02021 EAL24139 EAW76805 EAW76806 P63211 AF493869 AAM12583 BC029367 AAH29367 CR456912 CAG33193 DQ892560 ABM83486 DQ895775 ABM86701 S62027 AAB26896 NM_021955 NP_068774 |
Function | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
Tissue Specificity | Retinal rod outer segment. |
Top Pathways | Glutamatergic synapse, Dopaminergic synapse, GABAergic synapse, Morphine addiction, PI3K-Akt signaling pathway |
G γ 1 CRISPR/Cas9 KO Plasmid (h) - sc-409619 from Santa Cruz Biotechnology
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G γ 1 HDR Plasmid (h) - sc-409619-HDR from Santa Cruz Biotechnology
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G γ 1 Double Nickase Plasmid (h) - sc-409619-NIC from Santa Cruz Biotechnology
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G γ 1 Double Nickase Plasmid (h2) - sc-409619-NIC-2 from Santa Cruz Biotechnology
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G γ 1 CRISPR Activation Plasmid (h) - sc-409619-ACT from Santa Cruz Biotechnology
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G γ 1 CRISPR Activation Plasmid (h2) - sc-409619-ACT-2 from Santa Cruz Biotechnology
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G γ 1 Lentiviral Activation Particles (h) - sc-409619-LAC from Santa Cruz Biotechnology
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G γ 1 Lentiviral Activation Particles (h2) - sc-409619-LAC-2 from Santa Cruz Biotechnology
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G γ 1 siRNA (h) - sc-43774 from Santa Cruz Biotechnology
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G γ 1 shRNA Plasmid (h) - sc-43774-SH from Santa Cruz Biotechnology
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G γ 1 shRNA (h) Lentiviral Particles - sc-43774-V from Santa Cruz Biotechnology
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G γ 1 siRNA (h2) - sc-43801 from Santa Cruz Biotechnology
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G γ 1 shRNA Plasmid (h2) - sc-43801-SH from Santa Cruz Biotechnology
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G γ 1 shRNA (h2) Lentiviral Particles - sc-43801-V from Santa Cruz Biotechnology
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GNGT1 RNAi - H00002792-R01 from Novus Biologicals
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MISSION® esiRNA - EHU130351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9433 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9433 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01953 from Sigma-Aldrich
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GNGT1 siRNA (Human) - CRH1863 from Cohesion Biosciences
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GNGT1 - MBS8210644 from MyBioSource
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shRNA set against Human GNGT1 (NM_021955.3) - SHH304946 from Creative biogene
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shRNA set against Human GNGT1(NM_021955.3) - SHH092945 from Creative biogene
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Human GNGT1 siRNA - orb262365 from Biorbyt
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GNGT1 shRNA Plasmid (Human) - CHH1863 from Cohesion Biosciences
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