| Gene Symbol | GNGT1 |
|---|---|
| Entrez Gene | 2792 |
| Alt Symbol | GNG1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 |
| Other Description | guanine nucleotide-binding protein G(T) subunit gamma-T1|transducin gamma chain |
| Swissprots | Q16026 O43835 A4D1H2 Q08447 Q6LCP6 P63211 |
| Accessions | AAB92386 AAB92387 AAD13931 AAS02021 EAL24139 EAW76805 EAW76806 P63211 AF493869 AAM12583 BC029367 AAH29367 CR456912 CAG33193 DQ892560 ABM83486 DQ895775 ABM86701 S62027 AAB26896 NM_021955 NP_068774 |
| Function | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. |
| Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
| Tissue Specificity | Retinal rod outer segment. |
| Top Pathways | Glutamatergic synapse, Dopaminergic synapse, GABAergic synapse, Morphine addiction, PI3K-Akt signaling pathway |