| Gene Symbol |
COMMD9
|
| Entrez Gene |
29099
|
| Alt Symbol |
HSPC166
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
COMM domain containing 9
|
| Other Description |
COMM domain-containing protein 9
|
| Swissprots |
Q96FI2 Q9P000 Q9H0R0 E9PAN2
|
| Accessions |
EAW68128 EAW68129 EAW68130 Q9P000 AF161515 AAF29130 AI090006 AK055668 BAG51551 AK223213 BAD96933 AK290065 BAF82754 AK295590 BAG58482 AK298978 BAG61072 AK314477 BAG37082 AL136688 CAB66623 AY542164 AAS22246 BC010892 AAH10892 BC092458 BC108685 BG702189 BI668465 BM172201 DA774131 DN601764 DQ892672 ABM83598 DQ895914 ABM86840 XM_011520033 XP_011518335 NM_001101653 NP_001095123 NM_001307932 NP_001294861 NM_001307937 NP_001294866 NM_014186 NP_054905
|
| Function |
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (PubMed:23637203). {ECO:0000269|PubMed:15799966, ECO:0000269|PubMed:23637203, ECO:0000305|PubMed:21778237}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:21778237}. Cytoplasmic vesicle {ECO:0000269|PubMed:21778237}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:15799966}.
|
![Western Blot: COMMD9 Overexpression Lysate (Adult Normal) [NBL1-09372] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for COMMD9.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7340_COMMD9%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09372-img0002.jpg)