Gene Symbol | COMMD9 |
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Entrez Gene | 29099 |
Alt Symbol | HSPC166 |
Species | Human |
Gene Type | protein-coding |
Description | COMM domain containing 9 |
Other Description | COMM domain-containing protein 9 |
Swissprots | Q96FI2 Q9P000 Q9H0R0 E9PAN2 |
Accessions | EAW68128 EAW68129 EAW68130 Q9P000 AF161515 AAF29130 AI090006 AK055668 BAG51551 AK223213 BAD96933 AK290065 BAF82754 AK295590 BAG58482 AK298978 BAG61072 AK314477 BAG37082 AL136688 CAB66623 AY542164 AAS22246 BC010892 AAH10892 BC092458 BC108685 BG702189 BI668465 BM172201 DA774131 DN601764 DQ892672 ABM83598 DQ895914 ABM86840 XM_011520033 XP_011518335 NM_001101653 NP_001095123 NM_001307932 NP_001294861 NM_001307937 NP_001294866 NM_014186 NP_054905 |
Function | May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (PubMed:23637203). {ECO:0000269|PubMed:15799966, ECO:0000269|PubMed:23637203, ECO:0000305|PubMed:21778237}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:21778237}. Cytoplasmic vesicle {ECO:0000269|PubMed:21778237}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:15799966}. |
COMMD9 CRISPR/Cas9 KO Plasmid (h) - sc-409907 from Santa Cruz Biotechnology
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COMMD9 HDR Plasmid (h) - sc-409907-HDR from Santa Cruz Biotechnology
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COMMD9 Double Nickase Plasmid (h) - sc-409907-NIC from Santa Cruz Biotechnology
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COMMD9 Double Nickase Plasmid (h2) - sc-409907-NIC-2 from Santa Cruz Biotechnology
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COMMD9 CRISPR Activation Plasmid (h) - sc-409907-ACT from Santa Cruz Biotechnology
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COMMD9 CRISPR Activation Plasmid (h2) - sc-409907-ACT-2 from Santa Cruz Biotechnology
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COMMD9 Lentiviral Activation Particles (h) - sc-409907-LAC from Santa Cruz Biotechnology
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COMMD9 Lentiviral Activation Particles (h2) - sc-409907-LAC-2 from Santa Cruz Biotechnology
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COMMD9 siRNA (h) - sc-96510 from Santa Cruz Biotechnology
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COMMD9 shRNA Plasmid (h) - sc-96510-SH from Santa Cruz Biotechnology
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COMMD9 shRNA (h) Lentiviral Particles - sc-96510-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU033381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6422 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6422 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05853 from Sigma-Aldrich
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COMMD9 siRNA (Human) - CRH9190 from Cohesion Biosciences
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COMMD9 - MBS8214792 from MyBioSource
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shRNA set against Human COMMD9 (NM_014186.3) - SHH267665 from Creative biogene
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shRNA set against Human COMMD9(NM_014186.3) - SHG192247 from Creative biogene
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Human COMMD9 siRNA - orb269692 from Biorbyt
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COMMD9 shRNA Plasmid (Human) - CHH9190 from Cohesion Biosciences
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COMMD9 miRNA 3'UTR clone - MiUTR1H-02344 from Creative biogene
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