Gene Symbol | C14orf166 |
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Entrez Gene | 51637 |
Alt Symbol | CGI-99, CGI99, CLE, CLE7, LCRP369, RLLM1 |
Species | Human |
Gene Type | protein-coding |
Description | chromosome 14 open reading frame 166 |
Other Description | CLE7 homolog|RLL motif containing 1|UPF0568 protein C14orf166 |
Swissprots | Q9Y224 |
Accessions | EAW65659 EAW65660 EAW65661 Q9Y224 AF087877 AAP97177 AF100755 AAD43019 AF151857 AAD34094 AK312004 BAG34942 AY817175 AAV54070 BC001722 AAH01722 BF594675 DQ525179 ABF56619 EU446806 ABZ92335 NM_016039 NP_057123 |
Function | RNA-binding protein involved in modulation of mRNA transcription by Polymerase II. In case of infection by influenza virus A, is involved in viral replication. Component of the tRNA- splicing ligase complex and is required for tRNA ligation (PubMed:24870230). May be required for RNA transport (PubMed:24608264). {ECO:0000269|PubMed:16950395, ECO:0000269|PubMed:24608264, ECO:0000269|PubMed:24870230}. |
Subcellular Location | Nucleus. Cytoplasm, cytosol. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=May localize at the centrosome during mitosis. Shuttles between the cytosol and the nucleus: enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low (PubMed:24608264). {ECO:0000269|PubMed:24608264}. |
Tissue Specificity | Widely expressed. Expressed at high level in heart and skeletal muscle. Expressed at intermediate level in liver, pancreas, fetal brain and fetal lung. Weakly expressed in adult brain, adult lung, placenta, fetal liver and fetal kidney. Overexpressed in many brain tumors. {ECO:0000269|PubMed:15147888}. |
Human C14orf166 full length protein - ab87864 from Abcam
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C14orf166 Antibody Blocking Peptide - LS-E12260 from LifeSpan Bioscience
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C14orf166 Antibody Blocking Peptide - LS-E12261 from LifeSpan Bioscience
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C14orf166 Antibody Blocking Peptide - LS-E14151 from LifeSpan Bioscience
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Recombinant Human CLE7 homolog Protein - P3734 from Novus Biologicals
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C14orf166-Antibody-C-term-Blocking-Peptide - BP17346b from Abgent, a WuXi AppTec company
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Human C14orf166 Protein - abx060002 from Abbexa
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C14orf166 - P3734 from Acris Antibodies
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CLE; C14orf166 fusion protein - Ag13948 from Proteintech Group
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Recombinant Human C14ORF166, His-tagged - C14ORF166-26586TH from Creative Biomart
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Recombinant Human C14ORF166 - C14ORF166-26587TH from Creative Biomart
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Recombinant Human C14orf166, GST-tagged - C14orf166-11303H from Creative Biomart
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Recombinant Human UPF0568 protein C14orf166(C14orf166) - CSB-YP896684HU CSB-EP896684HU CSB-BP896684HU CSB-MP896684HU from Cusabio
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C14orf166 - TP300016 from Acris Antibodies
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C14orf166, Recombinant Protein - MBS8506870 from MyBioSource
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CLE7 homolog Recombinant Protein Antigen - NBP1-84498PEP from Novus Biologicals
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C14ORF166 Peptide, Human - M34GP01713H from Creative Peptides
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Human C14orf166 protein - orb54357 from Biorbyt
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C14ORF166 Recombinant Protein (Human) (OPCA04844) - OPCA04844 from Aviva Systems Biology
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