| Gene Symbol |
ST8SIA3
|
| Entrez Gene |
51046
|
| Alt Symbol |
SIAT8C, ST8SiaIII
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
|
| Other Description |
SIAT8-C|alpha-2,8-sialyltransferase 8C|alpha-2,8-sialyltransferase III|sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase|sialyltransferase 8C (alpha2,3Galbeta1,4GlcNAcalpha 2,8-sialyltransferase)|sialyltransferase St8Sia III|sialytransferase St8Sia III
|
| Swissprots |
A8K0F2 Q6B085 O43173 Q9NS41
|
| Accessions |
EAW63043 O43173 AB208996 BAD92233 AF003092 AAC15901 AF004668 AAB87642 AK054939 AK123291 AK289517 BAF82206 AK313047 BAG35879 BC074909 AAH74909 XM_011526019 XP_011524321 NM_015879 NP_056963
|
| Function |
May transfer sialic acid through alpha-2,8-linkages to alpha-2,3-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid. {ECO:0000269|PubMed:10766765, ECO:0000269|PubMed:9826427}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Expressed in fetal and adult brain and fetal liver. {ECO:0000269|PubMed:9826427}.
|
![Western Blot: ST8SIA3 Overexpression Lysate (Adult Normal) [NBL1-16506] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ST8SIA3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1391_ST8SIA3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16506-img0002.jpg)