Gene Symbol | ST8SIA3 |
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Entrez Gene | 51046 |
Alt Symbol | SIAT8C, ST8SiaIII |
Species | Human |
Gene Type | protein-coding |
Description | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
Other Description | SIAT8-C|alpha-2,8-sialyltransferase 8C|alpha-2,8-sialyltransferase III|sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase|sialyltransferase 8C (alpha2,3Galbeta1,4GlcNAcalpha 2,8-sialyltransferase)|sialyltransferase St8Sia III|sialytransferase St8Sia III |
Swissprots | A8K0F2 Q6B085 O43173 Q9NS41 |
Accessions | EAW63043 O43173 AB208996 BAD92233 AF003092 AAC15901 AF004668 AAB87642 AK054939 AK123291 AK289517 BAF82206 AK313047 BAG35879 BC074909 AAH74909 XM_011526019 XP_011524321 NM_015879 NP_056963 |
Function | May transfer sialic acid through alpha-2,8-linkages to alpha-2,3-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid. {ECO:0000269|PubMed:10766765, ECO:0000269|PubMed:9826427}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed in fetal and adult brain and fetal liver. {ECO:0000269|PubMed:9826427}. |
ST8Sia III CRISPR/Cas9 KO Plasmid (h) - sc-407120 from Santa Cruz Biotechnology
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ST8Sia III HDR Plasmid (h) - sc-407120-HDR from Santa Cruz Biotechnology
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ST8Sia III Double Nickase Plasmid (h) - sc-407120-NIC from Santa Cruz Biotechnology
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ST8Sia III Double Nickase Plasmid (h2) - sc-407120-NIC-2 from Santa Cruz Biotechnology
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ST8Sia III CRISPR Activation Plasmid (h) - sc-407120-ACT from Santa Cruz Biotechnology
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ST8Sia III CRISPR Activation Plasmid (h2) - sc-407120-ACT-2 from Santa Cruz Biotechnology
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ST8Sia III Lentiviral Activation Particles (h) - sc-407120-LAC from Santa Cruz Biotechnology
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ST8Sia III Lentiviral Activation Particles (h2) - sc-407120-LAC-2 from Santa Cruz Biotechnology
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ST8Sia III siRNA (h) - sc-76580 from Santa Cruz Biotechnology
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ST8Sia III shRNA Plasmid (h) - sc-76580-SH from Santa Cruz Biotechnology
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ST8Sia III shRNA (h) Lentiviral Particles - sc-76580-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN20676 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20676 from Sigma-Aldrich
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ST8SIA3 siRNA (Human) - CRH9476 from Cohesion Biosciences
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ST8SIA3 - MBS827333 from MyBioSource
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shRNA set against Human ST8SIA3 (NM_015879.2) - SHH419028 from Creative biogene
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shRNA set against Human ST8SIA3(NM_015879.2) - SHL039054 from Creative biogene
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Human ST8SIA3 siRNA - orb269978 from Biorbyt
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ST8SIA3 shRNA Plasmid (Human) - CHH9476 from Cohesion Biosciences
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ST8SIA3 miRNA 3'UTR clone - MiUTR1H-09960 from Creative biogene
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