| Gene Symbol |
ENOPH1
|
| Entrez Gene |
58478
|
| Alt Symbol |
E1, MASA, MST145, mtnC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
enolase-phosphatase 1
|
| Other Description |
2,3-diketo-5-methylthio-1-phosphopentane phosphatase|acireductone synthase|enolase-phosphatase E1
|
| Swissprots |
Q9UHY7 Q7Z4C5 Q9BVC2
|
| Accessions |
EAX05892 EAX05893 EAX05894 EAX05895 Q9UHY7 AF087881 AAP97181 AF113125 AAF14866 AF177286 AAQ13671 AK022656 BAB14160 AL110167 AL518796 AW470971 BC001317 AAH01317 BC065815 AAH65815 CN335976 CR457141 CAG33422 DA067292 DA347866 NM_001292017 NP_001278946 NM_021204 NP_067027 NR_120457
|
| Function |
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene). {ECO:0000255|HAMAP-Rule:MF_03117, ECO:0000269|PubMed:15843022}.
|
| Subcellular Location |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03117}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03117}.
|
| Top Pathways |
Cysteine and methionine metabolism
|
![Western Blot: MASA Overexpression Lysate (Adult Normal) [NBL1-10269] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MASA.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2575_MASA%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10269-img0002.jpg)