Gene Symbol | ENOPH1 |
---|---|
Entrez Gene | 58478 |
Alt Symbol | E1, MASA, MST145, mtnC |
Species | Human |
Gene Type | protein-coding |
Description | enolase-phosphatase 1 |
Other Description | 2,3-diketo-5-methylthio-1-phosphopentane phosphatase|acireductone synthase|enolase-phosphatase E1 |
Swissprots | Q9UHY7 Q7Z4C5 Q9BVC2 |
Accessions | EAX05892 EAX05893 EAX05894 EAX05895 Q9UHY7 AF087881 AAP97181 AF113125 AAF14866 AF177286 AAQ13671 AK022656 BAB14160 AL110167 AL518796 AW470971 BC001317 AAH01317 BC065815 AAH65815 CN335976 CR457141 CAG33422 DA067292 DA347866 NM_001292017 NP_001278946 NM_021204 NP_067027 NR_120457 |
Function | Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene). {ECO:0000255|HAMAP-Rule:MF_03117, ECO:0000269|PubMed:15843022}. |
Subcellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03117}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03117}. |
Top Pathways | Cysteine and methionine metabolism |
ENOPH1 CRISPR/Cas9 KO Plasmid (h) - sc-412907 from Santa Cruz Biotechnology
|
||||||||
ENOPH1 HDR Plasmid (h) - sc-412907-HDR from Santa Cruz Biotechnology
|
||||||||
ENOPH1 Double Nickase Plasmid (h) - sc-412907-NIC from Santa Cruz Biotechnology
|
||||||||
ENOPH1 Double Nickase Plasmid (h2) - sc-412907-NIC-2 from Santa Cruz Biotechnology
|
||||||||
ENOPH1 CRISPR Activation Plasmid (h) - sc-412907-ACT from Santa Cruz Biotechnology
|
||||||||
ENOPH1 CRISPR Activation Plasmid (h2) - sc-412907-ACT-2 from Santa Cruz Biotechnology
|
||||||||
ENOPH1 Lentiviral Activation Particles (h) - sc-412907-LAC from Santa Cruz Biotechnology
|
||||||||
ENOPH1 Lentiviral Activation Particles (h2) - sc-412907-LAC-2 from Santa Cruz Biotechnology
|
||||||||
ENOPH1 siRNA (h) - sc-88932 from Santa Cruz Biotechnology
|
||||||||
ENOPH1 shRNA Plasmid (h) - sc-88932-SH from Santa Cruz Biotechnology
|
||||||||
ENOPH1 shRNA (h) Lentiviral Particles - sc-88932-V from Santa Cruz Biotechnology
|
||||||||
MASA RNAi - H00058478-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU069981 from Sigma-Aldrich
|
||||||||
MISSION® Human Phosphatase - SIHP0158 from Sigma-Aldrich
|
||||||||
MISSION® Human Phosphatase - SIHP0159 from Sigma-Aldrich
|
||||||||
MISSION® Human Phosphatase - SIHP0157 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN7875 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7875 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR07912 from Sigma-Aldrich
|
||||||||
ENOPH1 siRNA (Human) - CRJ1712 from Cohesion Biosciences
|
||||||||
ENOPH1 - MBS8238925 from MyBioSource
|
||||||||
shRNA set against Human ENOPH1 (NM_021204.3) - SHH285861 from Creative biogene
|
||||||||
Human ENOPH1 siRNA - orb272213 from Biorbyt
|
||||||||
ENOPH1 shRNA Plasmid (Human) - CHJ1712 from Cohesion Biosciences
|
||||||||
ENOPH1 miRNA 3'UTR clone - MiUTR3H-14747 from Creative biogene
|