| Gene Symbol |
PRPF4
|
| Entrez Gene |
9128
|
| Alt Symbol |
HPRP4, HPRP4P, PRP4, Prp4p, RP70, SNRNP60
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
pre-mRNA processing factor 4
|
| Other Description |
PRP4 homolog|PRP4 pre-mRNA processing factor 4 homolog|PRP4/STK/WD splicing factor|U4/U6 small nuclear ribonucleoprotein Prp4|U4/U6 snRNP 60 kDa protein|WD splicing factor Prp4
|
| Swissprots |
O43445 Q96IK4 O43172 Q96DG2 O43864 Q5T1M8
|
| Accessions |
AAB87640 EAW87362 EAW87363 O43172 AB209797 BAD93034 AF016369 AAC51925 AK225056 AK313131 BAG35951 AW052006 AY572489 AAS78572 BC001588 AAH01588 BC007424 AAH07424 CA420073 CR457105 CAG33386 DA815191 EU176331 ABW03782 EU176673 ABW03474 U82756 AAC02261 XM_005252300 XP_005252357 XM_011519181 XP_011517483 NM_001244926 NP_001231855 NM_004697 NP_004688
|
| Function |
Participates in pre-mRNA splicing. Part of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome.
|
| Subcellular Location |
Nucleus speckle {ECO:0000250}. Note=Colocalizes with spliceosomal snRNPs. {ECO:0000250}.
|
| Top Pathways |
Spliceosome
|
![Western Blot: PRPF4 Overexpression Lysate (Adult Normal) [NBL1-14821] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PRPF4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4445_PRPF4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14821-img0002.jpg)