| Gene Symbol |
ARPC2
|
| Entrez Gene |
10109
|
| Alt Symbol |
ARC34, PNAS-139, PRO2446, p34-Arc
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
actin related protein 2/3 complex, subunit 2, 34kDa
|
| Other Description |
ARP2/3 protein complex subunit 34|actin-related protein 2/3 complex subunit 2|arp2/3 complex 34 kDa subunit
|
| Swissprots |
O15144 Q9P1D4 Q92801
|
| Accessions |
AAX93213 EAW70591 EAW70592 EAW70593 EAW70594 EAW70595 EAW70596 EAW70597 O15144 AF006085 AAB64190 AF279893 AAK07550 AK092520 AK093625 AK290268 BAF82957 BC000590 AAH00590 BG282181 BG765898 BT006898 AAP35544 CN291458 U50523 AAC50874 XM_011510470 XP_011508772 XM_011510471 XP_011508773 NM_005731 NP_005722 NM_152862 NP_690601
|
| Function |
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000269|PubMed:9230079}. Cell projection {ECO:0000269|PubMed:9230079}. Cell junction, synapse, synaptosome {ECO:0000250}.
|
| Top Pathways |
Pathogenic Escherichia coli infection, Fc gamma R-mediated phagocytosis, Bacterial invasion of epithelial cells, Salmonella infection, Regulation of actin cytoskeleton
|
![Western Blot: ARPC2 Overexpression Lysate (Adult Normal) [NBP2-05285] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ARPC2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5941_ARPC2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-05285-img0001.jpg)
![Western Blot: ARPC2 Overexpression Lysate (Adult Normal) [NBP2-07714] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ARPC2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9870_ARPC2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07714-img0001.jpg)