| Gene Symbol |
PLCH1
|
| Entrez Gene |
23007
|
| Alt Symbol |
PLCL3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phospholipase C, eta 1
|
| Other Description |
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1|PLC eta 1|PLC-L3|PLC-eta-1|phosphoinositide phospholipase C-eta-1|phospholipase C-eta-1|phospholipase C-eta1a|phospholipase C-eta1b|phospholipase C-like 3|phospholipase C-like protein 3
|
| Swissprots |
Q4KWH8 Q9H9U2 Q9UPT3 Q29RV9 Q86XK4 Q68CN0 Q4KWH9
|
| Accessions |
EAW78747 EAW78748 EAW78749 Q4KWH8 AB028992 BAA83021 AK022610 BAB14129 AK096620 AY691170 AAW22607 AY691171 AAW22608 BC043248 AAH43248 BC113950 AAI13951 CR749869 CAH18710 DA206803 XM_005247238 XP_005247295 XM_005247239 XP_005247296 XM_011512560 XP_011510862 XM_011512561 XP_011510863 XM_011512562 XP_011510864 XM_011512563 XP_011510865 XM_011512564 XP_011510866 XM_011512565 XP_011510867 XM_011512566 XP_011510868 XM_011512567 XP_011510869 NM_001130960 NP_001124432 NM_001130961 NP_001124433 NM_014996 NP_055811
|
| Function |
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by calcium-activated phosphatidylinositol-specific phospholipase C enzymes. {ECO:0000269|PubMed:15702972}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:15702972}. Membrane {ECO:0000269|PubMed:15702972}.
|
| Tissue Specificity |
Expressed in brain and to a lower extent in lung. In brain, it is found in cerebrum, cerebellum and spinal cord. {ECO:0000269|PubMed:15702972}.
|
| Top Pathways |
Inositol phosphate metabolism
|