PLCH1

Gene Symbol PLCH1
Entrez Gene 23007
Alt Symbol PLCL3
Species Human
Gene Type protein-coding
Description phospholipase C, eta 1
Other Description 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1|PLC eta 1|PLC-L3|PLC-eta-1|phosphoinositide phospholipase C-eta-1|phospholipase C-eta-1|phospholipase C-eta1a|phospholipase C-eta1b|phospholipase C-like 3|phospholipase C-like protein 3
Swissprots Q4KWH8 Q9H9U2 Q9UPT3 Q29RV9 Q86XK4 Q68CN0 Q4KWH9
Accessions EAW78747 EAW78748 EAW78749 Q4KWH8 AB028992 BAA83021 AK022610 BAB14129 AK096620 AY691170 AAW22607 AY691171 AAW22608 BC043248 AAH43248 BC113950 AAI13951 CR749869 CAH18710 DA206803 XM_005247238 XP_005247295 XM_005247239 XP_005247296 XM_011512560 XP_011510862 XM_011512561 XP_011510863 XM_011512562 XP_011510864 XM_011512563 XP_011510865 XM_011512564 XP_011510866 XM_011512565 XP_011510867 XM_011512566 XP_011510868 XM_011512567 XP_011510869 NM_001130960 NP_001124432 NM_001130961 NP_001124433 NM_014996 NP_055811
Function The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by calcium-activated phosphatidylinositol-specific phospholipase C enzymes. {ECO:0000269|PubMed:15702972}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15702972}. Membrane {ECO:0000269|PubMed:15702972}.
Tissue Specificity Expressed in brain and to a lower extent in lung. In brain, it is found in cerebrum, cerebellum and spinal cord. {ECO:0000269|PubMed:15702972}.
Top Pathways Inositol phosphate metabolism

PLC η1 siRNA (h) - sc-77989 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLC η1 shRNA Plasmid (h) - sc-77989-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLC η1 shRNA (h) Lentiviral Particles - sc-77989-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLCL3 RNAi - H00023007-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU099781 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU124411 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU087441 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU091331 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16928 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16928 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08340 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08340

PLCH1 siRNA (Human) - CRH7925 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PLCH1 (NM_014996.2) - SHH377240 from Creative biogene

Category siRNA
Species Reactivities Human

Human PLCH1 siRNA - orb268427 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PLCH1 shRNA Plasmid (Human) - CHH7925 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PLCH1 miRNA 3'UTR clone - MiUTR3H-12638 from Creative biogene

Species Reactivities Human

PLCH1 miRNA 3'UTR clone - MiUTR3H-12639 from Creative biogene

Species Reactivities Human
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