INPP5B

Gene Symbol	INPP5B
Entrez Gene	3633
Alt Symbol	5PTase
Species	Human
Gene Type	protein-coding
Description	inositol polyphosphate-5-phosphatase, 75kDa
Other Description	phosphoinositide 5-phosphatase|type II inositol 1,4,5-trisphosphate 5-phosphatase
Swissprots	Q658Q5 C9J6U5 P32019 Q5VSH0 Q6P6D4 Q6PD53 Q86YE1 Q5VSH1 Q5VSG9
Accessions	EAX07307 EAX07308 EAX07309 EAX07310 EAX07311 P32019 AK022846 BAG51126 AK093261 AK295062 BAG58111 AK310824 AL833055 CAH56301 BC042529 AAH42529 BC058932 AAH58932 BC062317 DA125087 DC398675 M74161 AAA79207 XM_005270835 XP_005270892 XM_006710619 XP_006710682 XM_006710621 XP_006710684 XM_011541387 XP_011539689 XM_011541388 XP_011539690 XM_011541389 XP_011539691 XM_011541390 XP_011539692 XM_011541391 XP_011539693 XM_011541392 XP_011539694 XM_011541393 XP_011539695 XR_946643 XR_946644 NM_001297434 NP_001284363 NM_005540 NP_005531
Function	Hydrolyzes phosphatidylinositol 4,5-bisphosphate (PtIns(4,5)P2) and the signaling molecule phosphatidylinositol 1,4,5-trisphosphate (PtIns(1,4,5)P3), and thereby modulates cellular signaling events. {ECO:0000269|PubMed:7721860}.
Subcellular Location	Cytoplasm, cytosol. Endoplasmic reticulum- Golgi intermediate compartment. Early endosome membrane. Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}. Golgi apparatus.
Tissue Specificity	Platelets.
Top Pathways	Inositol phosphate metabolism, Phosphatidylinositol signaling system

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

INPP5B CRISPR/Cas9 KO Plasmid (h) - sc-410542 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

INPP5B HDR Plasmid (h) - sc-410542-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

INPP5B Double Nickase Plasmid (h) - sc-410542-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

INPP5B Double Nickase Plasmid (h2) - sc-410542-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

INPP5B CRISPR Activation Plasmid (h) - sc-410542-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

INPP5B CRISPR Activation Plasmid (h2) - sc-410542-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

INPP5B Lentiviral Activation Particles (h) - sc-410542-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

INPP5B Lentiviral Activation Particles (h2) - sc-410542-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Type II 5-phosphatase siRNA (h) - sc-39096 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Type II 5-phoshatase shRNA Plasmid (h) - sc-39096-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Type II 5-phoshatase shRNA (h) Lentiviral Particles - sc-39096-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU102971 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® Human Phosphatase - SIHP0272 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0271 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0273 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN10692 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10692 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12739 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr12739

INPP5B siRNA (Human) - CRH2436 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

INPP5B RNAi - H00003633-R01 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

INPP5B - MBS8225401 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human INPP5B (NM_005540.2) - SHH319709 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human INPP5B(NM_005540.2) - SHL178598 from Creative biogene Category siRNA Species Reactivities Human

Human INPP5B siRNA - orb262938 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

INPP5B shRNA Plasmid (Human) - CHH2436 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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