INPP5B

Gene Symbol INPP5B
Entrez Gene 3633
Alt Symbol 5PTase
Species Human
Gene Type protein-coding
Description inositol polyphosphate-5-phosphatase, 75kDa
Other Description phosphoinositide 5-phosphatase|type II inositol 1,4,5-trisphosphate 5-phosphatase
Swissprots Q658Q5 C9J6U5 P32019 Q5VSH0 Q6P6D4 Q6PD53 Q86YE1 Q5VSH1 Q5VSG9
Accessions EAX07307 EAX07308 EAX07309 EAX07310 EAX07311 P32019 AK022846 BAG51126 AK093261 AK295062 BAG58111 AK310824 AL833055 CAH56301 BC042529 AAH42529 BC058932 AAH58932 BC062317 DA125087 DC398675 M74161 AAA79207 XM_005270835 XP_005270892 XM_006710619 XP_006710682 XM_006710621 XP_006710684 XM_011541387 XP_011539689 XM_011541388 XP_011539690 XM_011541389 XP_011539691 XM_011541390 XP_011539692 XM_011541391 XP_011539693 XM_011541392 XP_011539694 XM_011541393 XP_011539695 XR_946643 XR_946644 NM_001297434 NP_001284363 NM_005540 NP_005531
Function Hydrolyzes phosphatidylinositol 4,5-bisphosphate (PtIns(4,5)P2) and the signaling molecule phosphatidylinositol 1,4,5-trisphosphate (PtIns(1,4,5)P3), and thereby modulates cellular signaling events. {ECO:0000269|PubMed:7721860}.
Subcellular Location Cytoplasm, cytosol. Endoplasmic reticulum- Golgi intermediate compartment. Early endosome membrane. Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}. Golgi apparatus.
Tissue Specificity Platelets.
Top Pathways Inositol phosphate metabolism, Phosphatidylinositol signaling system

Type II 5-phosphatase (G-20) - sc-12307 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Type II 5-phosphatase (G-20): sc-12307. Western blot analysis of Type II 5-phosphatase expression in human platelet extract (A) and RAW 264.7 whole cell lysate (B).

Type II 5-phosphatase (Q-17) - sc-12308 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Type II 5-phosphatase (Q-17): sc-12308. Immunoperoxidase staining of formalin fixed, paraffin-embedded human gall bladder tissue showing cytoplasmic staining of glandular cells.

Anti-INPP5B antibody - ab95995 from Abcam

Prices $304.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-INPP5B antibody (ab95995) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

Anti-INPP5B antibody - ab70047 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-INPP5B antibody (ab70047) at 1/500 dilutionLane 1 : INPP5B-transfected 293T cell lysateLane 2 : non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 2500

Anti-INPP5B antibody - ab171992 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-INPP5B antibody (ab171992) at 1 µg/mlLane 1 : INPP5B transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysate

Anti-INPP5B Antibody (aa950-979, AP) - LS-C260259 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-INPP5B Antibody (aa950-979, APC) - LS-C260260 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-INPP5B Antibody (aa950-979, Biotin) - LS-C260261 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-INPP5B Antibody (aa950-979, FITC) - LS-C260262 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-INPP5B Antibody (aa950-979, Azide-free, HRP) - LS-C260263 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-INPP5B Antibody - LS-C308498 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-INPP5B Antibody (aa950-979, PE) - LS-C260264 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-INPP5B Antibody - LS-C311297 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-INPP5B Antibody (aa957-987) - LS-C322249 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-INPP5B Antibody (aa614-663) - LS-C81924 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-INPP5B Antibody (aa699-949) - LS-C186266 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Ca922 xenograft using INPP5B antibody at 1:100 dilution.

Anti-INPP5B Antibody (aa950-979) - LS-C165247 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
INPP5B antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.

INPP5B Antibody - NBP1-54719 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: INPP5B Antibody [NBP1-54719] - Hela cell lysate, concentration 0.2-1 ug/ml.

INPP5B Antibody - NBP1-89439 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: INPP5B Antibody [NBP1-89439] - Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.

INPP5B Antibody - NBP1-31705 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: INPP5B Antibody [NBP1-31705] - Sample (30 ug of whole cell lysate) A: H1299 7. 5% SDS PAGE; antibody diluted at 1:1000.

INPP5B Antibody - H00003633-B01 from Novus Biologicals

Host Mouse
Clonality Polyclonal
Western Blot: INPP5B Antibody [H00003633-B01] - analysis of INPP5B expression in transfected 293T cell line by INPP5B MaxPab polyclonal antibody (B01). Lane 1: INPP5B transfected lysate (85.00 KDa). Lane 2: Non-transfected lysate.

INPP5B Antibody - H00003633-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

INPP5B Antibody - H00003633-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: INPP5B Antibody [H00003633-D01P] - Analysis of INPP5B expression in transfected 293T cell line by INPP5B polyclonal antibody.Lane 1: INPP5B transfected lysate(85.00 KDa).Lane 2: Non-transfected lysate.

Anti-INPP5B antibody produced in rabbit - SAB2101164 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-INPP5B: <B>Cat. No.SAB2101164</B>: INPP5B in HeLa cell lysate with INPP5B antibody at 1.0 μg/mL.

Anti-INPP5B antibody produced in rabbit - HPA028803 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-INPP5B: <B>Cat. No. HPA028803</B>: Immunohistochemical staining of human small intestine shows moderate cytoplasmic positivity in glandular cells.
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