BCOR

Gene Symbol BCOR
Entrez Gene 54880
Alt Symbol ANOP2, MAA2, MCOPS2
Species Human
Gene Type protein-coding
Description BCL6 corepressor
Other Description BCL-6 corepressor|BCL-6 interacting corepressor
Swissprots Q9H233 Q8TEB4 Q6P4B6 Q9H232 Q96DB3 Q9HCJ7 Q6W2J9 Q29RF6 D3DWB4 Q9NXF2 D3DWB3 Q7Z2K7
Accessions EAW59425 EAW59426 EAW59427 EAW59428 EAW59429 EAW59430 Q6W2J9 AB046795 BAB13401 AF317391 AAG41429 AF317392 AAG41430 AK000292 BAA91061 AK056538 AK074286 BAB85037 AK095360 BAG53034 AK225581 AL698729 AY316592 AAR08265 BC009675 AAH09675 BC063536 AAH63536 BC114220 AAI14221 BC128387 AAI28388 BC128456 XM_005272616 XP_005272673 XM_005272618 XP_005272675 XM_005272619 XP_005272676 XM_005272620 XP_005272677 XM_006724536 XP_006724599 XM_011543929 XP_011542231 XM_011543930 XP_011542232 XM_011543931 XP_011542233 NM_001123383 NP_001116855 NM_001123384 NP_001116856 NM_001123385 NP_001116857 NM_017745 NP_060215 NM_001130139 NM_020926
Function Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence- specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2). {ECO:0000269|PubMed:10898795, ECO:0000269|PubMed:15004558, ECO:0000269|PubMed:18280243, ECO:0000269|PubMed:19578371, ECO:0000269|PubMed:23911289}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10898795}.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:10898795}.

BCOR-Over-expression-Lysate - LY12262a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag BCOR (arrow) using his tag antibody. 293T cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the LGALS8 gene

BCOR 293T Cell Transient Overexpression Lysate(Denatured) - H00054880-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

BCOR overexpression lysate - LY413571 from Acris Antibodies

Category Cell Lysate
Prices $480.00
Sizes 100 µg

BCOR overexpression lysate - LY426616 from Acris Antibodies

Category Cell Lysate
Prices $480.00
Sizes 100 µg

BCOR 293 Cell Lysate - 406551 from ABBIOTEC

Category Cell Lysate
Prices $672.00
Sizes 100 µg

BCOR Overexpression Lysate (Denatured) - H00054880-T01 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl
Species Human
BCOR transfected lysate.

BCOR Overexpression Lysate (Native) - NBL1-07956 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: BCOR Overexpression Lysate (Adult Normal) [NBL1-07956] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for BCOR.

BCOR Overexpression Lysate (Native) - NBP2-09415 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg

BCOR Over-expression Lysate Product - GWB-EA82D3 from Genway Biotech

Category Cell Lysate
Prices $756.00
Sizes 100 µg
Species Human

BCOR Overexpression Lysate (Native) - NBP2-06593 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg

Panoply™ Human BCOR Knockdown Stable Cell Line - CSC-DC001392 from Creative biogene

Category Cell Line
Species Human

Human BCOR Knockout Cell Line-HeLa - CSC-RT1414 from Creative biogene

Category Cell Line
Species Human

BCOR KO Cell Lysate-HeLa - CLKO-1264 from Creative biogene

Category Cell Lysate
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