| Gene Symbol |
Foxh1
|
| Entrez Gene |
14106
|
| Alt Symbol |
Fast1, Fast2, fast-1, fast-2
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
forkhead box H1
|
| Other Description |
FAST1 transcription factor|forkhead activin signal transducer 1|forkhead activin signal transducer 2|forkhead box protein H1
|
| Swissprots |
O88621 Q9R241 Q9QZL5
|
| Accessions |
EDL29601 O88621 AB221574 AF069303 AAC79808 AF079514 AAD12486 AF110506 AAD14683 AF177770 AAD55949 BC119156 AAI19157 BC137781 AAI37782 XM_006520436 XP_006520499 NM_007989 NP_032015
|
| Function |
Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element). {ECO:0000269|PubMed:10349617, ECO:0000269|PubMed:9702197, ECO:0000269|PubMed:9858566, ECO:0000269|Ref.4}.
|
| Subcellular Location |
Nucleus.
|