Gene Symbol | Foxh1 |
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Entrez Gene | 14106 |
Alt Symbol | Fast1, Fast2, fast-1, fast-2 |
Species | Mouse |
Gene Type | protein-coding |
Description | forkhead box H1 |
Other Description | FAST1 transcription factor|forkhead activin signal transducer 1|forkhead activin signal transducer 2|forkhead box protein H1 |
Swissprots | O88621 Q9R241 Q9QZL5 |
Accessions | EDL29601 O88621 AB221574 AF069303 AAC79808 AF079514 AAD12486 AF110506 AAD14683 AF177770 AAD55949 BC119156 AAI19157 BC137781 AAI37782 XM_006520436 XP_006520499 NM_007989 NP_032015 |
Function | Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element). {ECO:0000269|PubMed:10349617, ECO:0000269|PubMed:9702197, ECO:0000269|PubMed:9858566, ECO:0000269|Ref.4}. |
Subcellular Location | Nucleus. |
FAST-1/2 CRISPR/Cas9 KO Plasmid (m) - sc-420290 from Santa Cruz Biotechnology
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FAST-1/2 HDR Plasmid (m) - sc-420290-HDR from Santa Cruz Biotechnology
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FAST-1/2 Double Nickase Plasmid (m) - sc-420290-NIC from Santa Cruz Biotechnology
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FAST-1/2 Double Nickase Plasmid (m2) - sc-420290-NIC-2 from Santa Cruz Biotechnology
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FAST-1/2 CRISPR Activation Plasmid (m) - sc-420290-ACT from Santa Cruz Biotechnology
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FAST-1/2 CRISPR Activation Plasmid (m2) - sc-420290-ACT-2 from Santa Cruz Biotechnology
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FAST-1/2 Lentiviral Activation Particles (m) - sc-420290-LAC from Santa Cruz Biotechnology
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FAST-1/2 Lentiviral Activation Particles (m2) - sc-420290-LAC-2 from Santa Cruz Biotechnology
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FAST-1/2 siRNA (m) - sc-35363 from Santa Cruz Biotechnology
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FAST-1/2 shRNA Plasmid (m) - sc-35363-SH from Santa Cruz Biotechnology
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FAST-1/2 shRNA (m) Lentiviral Particles - sc-35363-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU015931 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN31504 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND31504 from Sigma-Aldrich
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FOXH1 siRNA (Mouse) - CRM1312 from Cohesion Biosciences
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FOXH1 - MBS8239301 from MyBioSource
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shRNA set against Mouse Foxh1 (NM_007989.3) - SHH296573 from Creative biogene
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shRNA set against Mouse Foxh1(NM_007989.3) - SHH066397 from Creative biogene
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Mouse FOXH1 siRNA - orb280788 from Biorbyt
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FOXH1 shRNA Plasmid (Mouse) - CHM1312 from Cohesion Biosciences
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FOXH1 miRNA 3'UTR clone - MiUTR1M-04775 from Creative biogene
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