| Gene Symbol |
U2af2
|
| Entrez Gene |
22185
|
| Alt Symbol |
65kDa
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
|
| Other Description |
U2 auxiliary factor 65 kDa subunit|U2 small nuclear ribonucleoprotein auxiliary factor (U2AF), 65 kDa|U2 snRNP auxiliary factor large subunit|splicing factor U2AF 65 kDa subunit
|
| Swissprots |
P26369
|
| Accessions |
EDL31286 EDL31287 P26369 AK078496 BAC37309 BC007487 AAH07487 BC043071 AAH43071 BC094451 AAH94451 BC106134 AAI06135 BU054258 BY663658 X64587 CAA45874 XM_006539727 XP_006539790 XM_006539728 XP_006539791 XM_006539730 XP_006539793 NM_001205231 NP_001192160 NM_133671 NP_598432
|
| Function |
Necessary for the splicing of pre-mRNA. By recruiting PRPF19 and the PRP19C/Prp19 complex/NTC/Nineteen complex to the RNA polymerase II C-terminal domain (CTD), and thereby pre-mRNA, may couple transcription to splicing. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron- less gene. {ECO:0000250|UniProtKB:P26368}.
|
| Subcellular Location |
Nucleus.
|
| Top Pathways |
Spliceosome
|