Gene Symbol | U2af2 |
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Entrez Gene | 22185 |
Alt Symbol | 65kDa |
Species | Mouse |
Gene Type | protein-coding |
Description | U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 |
Other Description | U2 auxiliary factor 65 kDa subunit|U2 small nuclear ribonucleoprotein auxiliary factor (U2AF), 65 kDa|U2 snRNP auxiliary factor large subunit|splicing factor U2AF 65 kDa subunit |
Swissprots | P26369 |
Accessions | EDL31286 EDL31287 P26369 AK078496 BAC37309 BC007487 AAH07487 BC043071 AAH43071 BC094451 AAH94451 BC106134 AAI06135 BU054258 BY663658 X64587 CAA45874 XM_006539727 XP_006539790 XM_006539728 XP_006539791 XM_006539730 XP_006539793 NM_001205231 NP_001192160 NM_133671 NP_598432 |
Function | Necessary for the splicing of pre-mRNA. By recruiting PRPF19 and the PRP19C/Prp19 complex/NTC/Nineteen complex to the RNA polymerase II C-terminal domain (CTD), and thereby pre-mRNA, may couple transcription to splicing. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron- less gene. {ECO:0000250|UniProtKB:P26368}. |
Subcellular Location | Nucleus. |
Top Pathways | Spliceosome |
U2AF65 CRISPR/Cas9 KO Plasmid (m) - sc-423572 from Santa Cruz Biotechnology
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U2AF65 HDR Plasmid (m) - sc-423572-HDR from Santa Cruz Biotechnology
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U2AF65 Double Nickase Plasmid (m) - sc-423572-NIC from Santa Cruz Biotechnology
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U2AF65 Double Nickase Plasmid (m2) - sc-423572-NIC-2 from Santa Cruz Biotechnology
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U2AF65 CRISPR Activation Plasmid (m) - sc-423572-ACT from Santa Cruz Biotechnology
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U2AF65 CRISPR Activation Plasmid (m2) - sc-423572-ACT-2 from Santa Cruz Biotechnology
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U2AF65 Lentiviral Activation Particles (m) - sc-423572-LAC from Santa Cruz Biotechnology
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U2AF65 Lentiviral Activation Particles (m2) - sc-423572-LAC-2 from Santa Cruz Biotechnology
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U2AF65 siRNA (m) - sc-37668 from Santa Cruz Biotechnology
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U2AF65 shRNA Plasmid (m) - sc-37668-SH from Santa Cruz Biotechnology
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U2AF65 shRNA (m) Lentiviral Particles - sc-37668-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU047701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN43774 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND43774 from Sigma-Aldrich
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U2AF2 siRNA (Mouse) - CRM4303 from Cohesion Biosciences
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U2AF2 - MBS8226738 from MyBioSource
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U2AF2 shRNA Plasmid (Mouse) - CHM4303 from Cohesion Biosciences
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