RHBDF2

Gene Symbol RHBDF2
Entrez Gene 79651
Alt Symbol RHBDL5, RHBDL6, TEC, TOC, TOCG, iRhom2
Species Human
Gene Type protein-coding
Description rhomboid 5 homolog 2 (Drosophila)
Other Description inactive rhomboid protein 2|rhomboid family member 2|rhomboid veinlet-like protein 5|rhomboid veinlet-like protein 6
Swissprots Q6PJF5 Q9H6E9 Q5YGQ8 Q5U607 A6NEM3 A8K801
Accessions EAW89401 EAW89402 EAW89403 EAW89404 Q6PJF5 AK025994 BAB15310 AK057882 AK074034 BAB84860 AK225684 AK292135 BAF84824 AK292166 BAF84855 AK303434 BAH13960 AL833680 AY500247 AAS77567 BC016034 AAH16034 BC035829 AAH35829 BE076010 BM801831 BP284970 BP288209 DC337840 DC348660 XM_005257669 XP_005257726 XM_005257670 XP_005257727 XM_011525249 XP_011523551 XM_011525250 XP_011523552 XM_011525251 XP_011523553 XM_011525252 XP_011523554 NM_001005498 NP_001005498 NM_024599 NP_078875
Function Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration (By similarity). {ECO:0000250}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell membrane {ECO:0000269|PubMed:22265016}.
Tissue Specificity Found in the epidermis and esophageal epithelium. {ECO:0000269|PubMed:22265016}.

RHBDL6 (T-12) - sc-138585 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
RHBDL6 (T-12): sc-138585. Western blot analysis of RHBDL6 expression in CCRF-CEM whole cell lysate.

RHBDL6 (S-13) - sc-138584 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

RHBDL6 (E-12) - sc-138583 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-RHBDF2 antibody - ab116139 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-RHBDF2 antibody (ab116139) at 1/100 dilution + CEM cell line lysate at 35 µg

Anti-RHBDF2 antibody - N-terminal - ab187389 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RHBDF2 antibody - N-terminal (ab187389) at 1/1000 dilutionLane 1 : Mouse thymus total cell extractLane 2 : HeLa total cell extractLane 3 : Jurkat total cell extract

Anti-RHBDF2 Antibody (aa80-109, AP) - LS-C268204 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RHBDF2 Antibody (aa80-109, APC) - LS-C268205 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RHBDF2 Antibody (aa80-109, Biotin) - LS-C268207 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RHBDF2 Antibody (aa80-109, FITC) - LS-C268208 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RHBDF2 Antibody (aa80-109, PE) - LS-C268210 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RHBDF2 Antibody (aa80-109, Azide-free, HRP) - LS-C268209 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RHBDF2 Antibody (aa79-109) - LS-C324655 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RHBDF2 Antibody (aa80-109) - LS-C162586 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
RHBDF2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skin tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Tec Antibody (663921) - MAB6519 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 663921
Western blot shows lysates of Daudi human Burkitt's lymphoma cell line, Ramos human Burkitt's lymphoma cell line, K562 human chronic myelogenous leukemia cell line, Jurkat human acute T cell leukemia cell line, and BaF3 mouse pro-B cell line. PVDF Membrane was probed with 1 µg/mL of Human/Mouse Tec Monoclonal Antibody (Catalog # MAB6519) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for Tec at approximately 66 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Tec Antibody - NBP1-87206 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Tec Antibody [NBP1-87206] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

RHBDF2 Antibody - NBP1-82126 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: RHBDF2 Antibody [NBP1-82126] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli.

Tec Antibody (3A5) - NBP1-51576 from Novus Biologicals

Prices $309.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3A5
Western Blot: Tec Antibody (3A5) [NBP1-51576] - Western blot analysis using TEC mouse mAb against TEC (aa90-240)-hIgGFc transfected HEK293 cell lysate (1).

Anti-RHBDF2 antibody produced in rabbit - HPA018080 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RHBDF2: <B>Cat. No. HPA018080</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human duodenum shows strong cytoplasmic positivity in goblet cells.

RHBDF2-Antibody-N-term - AP13588a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysate from MCF-7 cell line, using RHBDF2 Antibody (N-term)(Cat. #AP13588a). AP13588a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.

RHBDF2 Antibody - N-terminal region (OAAB09889) - OAAB09889 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

TEC antibody - orb69042 from Biorbyt

Prices $332.00
Sizes 100 μl
Host Mouse
Clonality Monoclonal
Clone 3A5
Western blot analysis of TEC-hIgGFc transfected HEK293 cell lysate using TEC antibody.

TEC antibody - 10R-1859 from Fitzgerald

Prices $295.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3A5

RHBDF2 antibody - orb31675 from Biorbyt

Prices $187.00, $383.00
Sizes 80 μl (Trial size), 400 μl
Host Rabbit
Clonality Polyclonal
Western blot analysis of CEM cell line lysates (35ug/lane) using RHBDF2 antibody

RHBDF2 Antibody - abx027486 from Abbexa

Host Rabbit
Clonality Polyclonal

TEC antibody - abx011600 from Abbexa

Host Mouse
Clonality Monoclonal
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