Gene Symbol | ASCC3 |
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Entrez Gene | 10973 |
Alt Symbol | ASC1p200, HELIC1, RNAH |
Species | Human |
Gene Type | protein-coding |
Description | activating signal cointegrator 1 complex subunit 3 |
Other Description | ASC-1 complex subunit P200|RNA helicase family|helicase, ATP binding 1|trip4 complex subunit p200 |
Swissprots | Q9H1I9 O43738 E7EW23 Q9H5A2 Q5VTN2 Q4G1A0 Q8N3C0 Q9NTR0 |
Accessions | EAW48449 EAW48450 Q8N3C0 AA788717 AI803859 AJ223948 CAA11679 AK023189 AK299117 BAG61172 AK307903 AK315197 BAG37637 AL834463 CAD39122 AM393382 CAL38260 AY013288 AAG45474 BC014358 BC026066 AAH26066 BC039857 BC050681 AAH50681 BC125211 AAI25212 BC125212 AAI25213 BC130038 BC150215 AAI50216 BU686034 BX415629 CN255848 XM_011535394 XP_011533696 XM_011535395 XP_011533697 XM_011535396 XP_011533698 NM_001284271 NP_001271200 NM_006828 NP_006819 NM_022091 NP_071374 |
Function | 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3, enabling ALKHB3 to process alkylated N3- methylcytosine (3mC) within double-stranded regions. Enhances NF- kappa-B, SRF and AP1 transactivation. {ECO:0000269|PubMed:22055184}. |
Subcellular Location | Nucleus. Cytoplasm. |
Tissue Specificity | Ubiquitous. |
HELIC1 (G-19) - sc-68558 from Santa Cruz Biotechnology
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HELIC1 (S-20) - sc-68559 from Santa Cruz Biotechnology
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Anti-ASCC3 antibody - ab168810 from Abcam
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Anti-ASCC3 antibody - ab122179 from Abcam
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Anti-ASCC3 antibody - ab122180 from Abcam
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Anti-ASCC3 antibody - ab122181 from Abcam
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Anti-ASCC3 Antibody (aa175-225) - LS-C290659 from LifeSpan Bioscience
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Anti-ASCC3 Antibody (aa2152-2202) - LS-C290660 from LifeSpan Bioscience
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ASCC3 Antibody - NBP1-88829 from Novus Biologicals
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ASCC3 Antibody - NBP1-88854 from Novus Biologicals
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ASCC3 Antibody - NBP1-88853 from Novus Biologicals
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Anti-ASCC3 antibody produced in rabbit - HPA031608 from Sigma-Aldrich
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Anti-ASCC3 antibody produced in rabbit - HPA031609 from Sigma-Aldrich
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Anti-ASCC3 antibody produced in rabbit - HPA031610 from Sigma-Aldrich
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Anti -ASCC3 (Activating Signal Cointegor 1 Complex Subunit 3, RNAH, HELIC1, ASC1p200) - 209619 from USBiological Life Science
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ASCC3 Polyclonal Antibody - A4469 from ABclonal
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ASCC3 antibody - 70R-15862 from Fitzgerald
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Activating Signal CointegRator 1 Complex Subunit 3 Antibody - abx110783 from Abbexa
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ASCC3 Antibody - abx003342 from Abbexa
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ASCC3 antibody - 17627-1-AP from Acris Antibodies
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Anti-ASCC3, Polyclonal Antibody - 25-A4469 from ARP American Research Products
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ASCC3 antibody - 17627-1-AP from Proteintech Group
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ASCC3 antibody - STJ22699 from St John's Laboratory Ltd
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ASCC3 - A4469 from NeoScientific
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ASCC3 - MBS128793 from MyBioSource
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