ASCC3

Gene Symbol	ASCC3
Entrez Gene	10973
Alt Symbol	ASC1p200, HELIC1, RNAH
Species	Human
Gene Type	protein-coding
Description	activating signal cointegrator 1 complex subunit 3
Other Description	ASC-1 complex subunit P200|RNA helicase family|helicase, ATP binding 1|trip4 complex subunit p200
Swissprots	Q9H1I9 O43738 E7EW23 Q9H5A2 Q5VTN2 Q4G1A0 Q8N3C0 Q9NTR0
Accessions	EAW48449 EAW48450 Q8N3C0 AA788717 AI803859 AJ223948 CAA11679 AK023189 AK299117 BAG61172 AK307903 AK315197 BAG37637 AL834463 CAD39122 AM393382 CAL38260 AY013288 AAG45474 BC014358 BC026066 AAH26066 BC039857 BC050681 AAH50681 BC125211 AAI25212 BC125212 AAI25213 BC130038 BC150215 AAI50216 BU686034 BX415629 CN255848 XM_011535394 XP_011533696 XM_011535395 XP_011533697 XM_011535396 XP_011533698 NM_001284271 NP_001271200 NM_006828 NP_006819 NM_022091 NP_071374
Function	3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3, enabling ALKHB3 to process alkylated N3- methylcytosine (3mC) within double-stranded regions. Enhances NF- kappa-B, SRF and AP1 transactivation. {ECO:0000269|PubMed:22055184}.
Subcellular Location	Nucleus. Cytoplasm.
Tissue Specificity	Ubiquitous.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HELIC1 CRISPR/Cas9 KO Plasmid (h) - sc-409485 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

HELIC1 HDR Plasmid (h) - sc-409485-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

HELIC1 Double Nickase Plasmid (h) - sc-409485-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

HELIC1 Double Nickase Plasmid (h2) - sc-409485-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

HELIC1 CRISPR Activation Plasmid (h) - sc-409485-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

HELIC1 CRISPR Activation Plasmid (h2) - sc-409485-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

HELIC1 Lentiviral Activation Particles (h) - sc-409485-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

HELIC1 Lentiviral Activation Particles (h2) - sc-409485-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

HELIC1 siRNA (h) - sc-75241 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

HELIC1 shRNA Plasmid (h) - sc-75241-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

HELIC1 shRNA (h) Lentiviral Particles - sc-75241-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ASCC3 RNAi - H00010973-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU097531 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU089691 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU096621 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3587 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3587 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

ASCC3 siRNA (Human) - CRH7492 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ASCC3 RNAi - H00010973-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

ASCC3 - MBS8200413 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human ASCC3 (NM_022091.3) - SHH241366 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human ASCC3(NM_006828.2) - SHG077131 from Creative biogene Category siRNA Species Reactivities Human

ASCC3 shRNA Plasmid (Human) - CHH7492 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ASCC3 miRNA 3'UTR clone - MiUTR1H-00627 from Creative biogene Species Reactivities Human

ASCC3 miRNA 3'UTR clone - MiUTR1H-00628 from Creative biogene Species Reactivities Human

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