| Gene Symbol |
CHRNA6
|
| Entrez Gene |
8973
|
| Alt Symbol |
CHNRA6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cholinergic receptor, nicotinic, alpha 6 (neuronal)
|
| Other Description |
acetylcholine receptor, nicotinic, alpha 6 (neuronal)|cholinergic receptor, nicotinic, alpha polypeptide 6|neuronal acetylcholine receptor subunit alpha-6
|
| Swissprots |
Q15825 B4DQH1 B2R8V4
|
| Accessions |
BAC06855 CCQ43252 EAW63207 Q15825 AK298798 BAG60933 AK313521 BAG36301 BC014456 AAH14456 DC307404 HQ448331 ADQ32811 U62435 AAB40113 Y16282 CAA76155 NM_001199279 NP_001186208 NM_004198 NP_004189
|
| Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
|
| Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Nicotine addiction, Neuroactive ligand-receptor interaction
|
![Western Blot: CHRNA6 Overexpression Lysate (Adult Normal) [NBP2-04267] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CHRNA6.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4219_CHRNA6%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04267-img0001.jpg)