| Gene Symbol |
TMEFF1
|
| Entrez Gene |
8577
|
| Alt Symbol |
C9orf2, CT120.1, H7365, TR-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane protein with EGF-like and two follistatin-like domains 1
|
| Other Description |
cancer/testis antigen family 120, member 1|tomoregulin-1|transmembrane protein with EGF-like and one follistatin-like domain
|
| Swissprots |
Q8N3T8 Q13086 Q8IYR6
|
| Accessions |
EAW58936 Q8IYR6 BC021991 BC035056 AAH35056 BF436262 DN602026 DQ891732 ABM82658 DQ894909 ABM85835 NM_003692 NP_003683
|
| Function |
May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers. {ECO:0000250, ECO:0000269|PubMed:12743596}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:12743596}; Single-pass type I membrane protein {ECO:0000269|PubMed:12743596}.
|
| Tissue Specificity |
Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues. {ECO:0000269|PubMed:12743596}.
|
![Western Blot: TMEFF1 Overexpression Lysate (Adult Normal) [NBL1-16987] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TMEFF1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/13641_TMEFF1%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-16987-img0002.jpg)