| Gene Symbol |
TTPA
|
| Entrez Gene |
7274
|
| Alt Symbol |
ATTP, AVED, TTP1, alphaTTP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tocopherol (alpha) transfer protein
|
| Other Description |
alpha-TTP|alpha-tocopherol transfer protein|tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency)
|
| Swissprots |
P49638 Q71V64
|
| Accessions |
EAW86863 P49638 BC041784 BC058000 AAH58000 D49488 BAA08449 HQ447611 ADQ32097 U21938 AAA64309 XM_006716468 XP_006716531 NM_000370 NP_000361
|
| Function |
Binds alpha-tocopherol, enhances its transfer between separate membranes, and stimulates its release from liver cells (PubMed:7887897). Binds both phosphatidylinol 3,4-bisphosphate and phosphatidylinol 4,5-bisphosphate; the resulting conformation change is important for the release of the bound alpha-tocopherol (By similarity). {ECO:0000250, ECO:0000269|PubMed:7887897}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:7887897}.
|