| Gene Symbol |
SLC27A6
|
| Entrez Gene |
28965
|
| Alt Symbol |
ACSVL2, FACVL2, FATP6, VLCS-H1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 27 (fatty acid transporter), member 6
|
| Other Description |
FATP-6|VLCSH1|fatty acid transport protein 6|fatty-acid-Coenzyme A ligase, very long-chain 2|hVLCS-H1|long-chain fatty acid transport protein 6|solute carrier family 27 member 6|very long-chain acyl-CoA synthetase homolog 1
|
| Swissprots |
Q86YF6 Q9Y2P4 Q6IAM5 Q7Z6E6
|
| Accessions |
EAW62387 Q9Y2P4 AA614135 AF064254 AAD29443 AK313456 BAG36243 AL833117 BC041945 AAH41945 BX537383 CAD97625 CR457129 CAG33410 XM_005271967 XP_005272024 XM_005271968 XP_005272025 XM_005271969 XP_005272026 XM_005271970 XP_005272027 XM_011543348 XP_011541650 NM_001017372 NP_001017372 NM_014031 NP_054750
|
| Function |
Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Thought to function as the predominant fatty acid protein transporter in heart. {ECO:0000269|PubMed:12556534}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell membrane, sarcolemma {ECO:0000250}. Note=In heart is exclusively located on the sarcolemma in areas juxtaposed with small blood vessels where it colocalizes CD36. {ECO:0000250}.
|
| Tissue Specificity |
Strongly expressed in heart and localizes to cardiac myocytes. Expressed at moderate levels in placenta, testis, and adrenal glands. Expressed at very low levels in kidney, bladder and uterus. {ECO:0000269|PubMed:12556534}.
|
| Top Pathways |
PPAR signaling pathway
|