| Gene Symbol | ATP6V0B |
|---|---|
| Entrez Gene | 533 |
| Alt Symbol | ATP6F, HATPL, VMA16 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b |
| Other Description | ATPase, H+ transporting, lysosomal, 21-KD, V0 subunit C-prime, prime|ATPase, H+ transporting, lysosomal, subunit F|H(+)-transporting two-sector ATPase, subunit F|V-ATPase 21 kDa proteolipid subunit|V-ATPase subunit c''|V-type proton ATPase 21 kDa proteolipid subunit|vacuolar ATP synthase 21 kDa proteolipid subunit|vacuolar proton pump 21 kDa proteolipid subunit |
| Swissprots | Q6IB32 Q99437 D3DPY5 |
| Accessions | BAC02927 EAX07066 EAX07067 EAX07068 EAX07069 Q99437 AI439545 BC000423 AAH00423 BC005876 AAH05876 BC042664 BC053601 BG475609 BG831921 BI770034 BP250477 BT007151 AAP35815 CR456972 CAG33253 D89052 BAA13753 L05089 AAC15853 NM_001039457 NP_001034546 NM_001294333 NP_001281262 NM_004047 NP_004038 |
| Function | Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. |
| Subcellular Location | Vacuole membrane; Multi-pass membrane protein. |
| Tissue Specificity | Ubiquitous. |
| Top Pathways | Tuberculosis, Synaptic vesicle cycle, Rheumatoid arthritis, Phagosome, Lysosome |