Gene Symbol |
ATP6V0B
|
Entrez Gene |
533
|
Alt Symbol |
ATP6F, HATPL, VMA16
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
|
Other Description |
ATPase, H+ transporting, lysosomal, 21-KD, V0 subunit C-prime, prime|ATPase, H+ transporting, lysosomal, subunit F|H(+)-transporting two-sector ATPase, subunit F|V-ATPase 21 kDa proteolipid subunit|V-ATPase subunit c''|V-type proton ATPase 21 kDa proteolipid subunit|vacuolar ATP synthase 21 kDa proteolipid subunit|vacuolar proton pump 21 kDa proteolipid subunit
|
Swissprots |
Q6IB32 Q99437 D3DPY5
|
Accessions |
BAC02927 EAX07066 EAX07067 EAX07068 EAX07069 Q99437 AI439545 BC000423 AAH00423 BC005876 AAH05876 BC042664 BC053601 BG475609 BG831921 BI770034 BP250477 BT007151 AAP35815 CR456972 CAG33253 D89052 BAA13753 L05089 AAC15853 NM_001039457 NP_001034546 NM_001294333 NP_001281262 NM_004047 NP_004038
|
Function |
Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
|
Subcellular Location |
Vacuole membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Ubiquitous.
|
Top Pathways |
Tuberculosis, Synaptic vesicle cycle, Rheumatoid arthritis, Phagosome, Lysosome
|