Gene Symbol | MAPRE1 |
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Entrez Gene | 22919 |
Alt Symbol | EB1 |
Species | Human |
Gene Type | protein-coding |
Description | microtubule-associated protein, RP/EB family, member 1 |
Other Description | APC-binding protein EB1|adenomatous polyposis coli-binding protein EB1|end-binding protein 1|microtubule-associated protein RP/EB family member 1 |
Swissprots | E1P5M8 B2R6I7 Q15691 Q3KQS8 |
Accessions | EAW76348 EAW76349 Q15691 AK297273 BAG59745 AK310817 AK312590 BAG35484 BC040410 BC106068 AAI06069 BC109281 AAI09282 BC128442 AAI28443 BJ992159 BM983860 EU832776 ACE87787 GQ129296 ACT64430 U24166 AAC09471 XM_011528696 XP_011526998 NM_012325 NP_036457 |
Function | Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration. {ECO:0000269|PubMed:12388762, ECO:0000269|PubMed:16109370, ECO:0000269|PubMed:19632184, ECO:0000269|PubMed:21646404}. |
Subcellular Location | Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Associated with the microtubule network at the growing distal tip of microtubules. Also enriched at the centrosome. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:10644998}. |
Human MAPRE1 full length protein - ab101824 from Abcam
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Human MAPRE1 full length protein - ab182821 from Abcam
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Human MAPRE1 peptide - ab73305 from Abcam
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MAPRE1 / EB1 Antibody Blocking Peptide - LS-E22549 from LifeSpan Bioscience
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MAPRE1 / EB1 Antibody Blocking Peptide - LS-E8447 from LifeSpan Bioscience
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Recombinant Human MAPRE1 Protein - H00022919-P01 from Novus Biologicals
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MAPRE1 Partial Recombinant Protein - H00022919-Q01 from Novus Biologicals
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Recombinant Human MAPRE1 Protein - NBP1-50935 from Novus Biologicals
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MAPRE1-Antibody-C-term-Blocking-Peptide - BP6770e from Abgent, a WuXi AppTec company
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MAPRE1-Antibody-Center-Blocking-Peptide - BP6770c from Abgent, a WuXi AppTec company
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MAPRE1-Antibody-C-term-Blocking-Peptide - BP6770b from Abgent, a WuXi AppTec company
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MAPRE1-Antibody-N-term-Blocking-peptide - BP6770a from Abgent, a WuXi AppTec company
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MAPRE1 Protein (OPPA00044) - OPPA00044 from Aviva Systems Biology
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Human MAPRE1 protein - orb168780 from Biorbyt
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MAPRE1 protein (His tag) - 80R-1610 from Fitzgerald
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MAPRE1 (1-268, His-tag) - AR09791PU-L from Acris Antibodies
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MAPRE1 (1-268, His-tag) - AR09791PU-N from Acris Antibodies
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MAPRE1 - H00022919-P01-10 from Acris Antibodies
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MAPRE1 - H00022919-P01-25 from Acris Antibodies
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MAPRE1 - H00022919-Q01-10 from Acris Antibodies
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MAPRE1 - H00022919-Q01-25 from Acris Antibodies
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MAPRE1, 1-268aa, Human, His tag, E.coli - 01-MAPR-E1 from ARP American Research Products
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EB1 fusion protein - Ag12092 from Proteintech Group
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MAPRE1 Human - PRPS-065 from NeoScientific
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MAPRE1, 1-268aa, Recombinant Protein - GWB-P1187D from Genway Biotech
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