| Gene Symbol |
CRB2
|
| Entrez Gene |
286204
|
| Alt Symbol |
FSGS9, VMCKD
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
crumbs family member 2
|
| Other Description |
crumbs homolog 2|crumbs-like protein 2|protein crumbs homolog 2
|
| Swissprots |
Q5JS43 Q0QD46 Q6ZTA9 Q5JS41 Q6ZWI6 Q5IJ48 A2A3N4
|
| Accessions |
EAW87567 EAW87568 Q5IJ48 AK095783 BAC04626 AK123000 AK124819 AK126775 BAC86684 AY720432 AAU14134 CX871675 DA240339 DQ426866 ABD90532 XM_005251934 XP_005251991 XM_011518556 XP_011516858 XM_011518557 XP_011516859 XM_011518558 XP_011516860 NM_173689 NP_775960 NR_104603
|
| Function |
May play a role in polarized cells morphogenesis.
|
| Subcellular Location |
Isoform 1: Cell membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Expressed in retina, fetal eye and brain. Also expressed in kidney, ARPE-19 and RPE/choroid cell lines, and at low levels in lung, placenta, and heart. {ECO:0000269|PubMed:15851977}.
|
| Top Pathways |
Hippo signaling pathway
|