PDS5A

Gene Symbol PDS5A
Entrez Gene 23244
Alt Symbol PIG54, SCC-112, SCC112
Species Human
Gene Type protein-coding
Description PDS5 cohesin associated factor A
Other Description PDS5, regulator of cohesion maintenance, homolog A|cell proliferation-inducing gene 54 protein|sister chromatid cohesion protein 112|sister chromatid cohesion protein PDS5 homolog A
Swissprots Q9Y4D4 Q8N7J4 Q68DF7 Q8NG14 Q29RF7 Q2TTR5
Accessions CDM63448 EAW92952 EAW92953 EAW92954 EAW92955 Q29RF7 AB014548 BAA31623 AB621803 BAK64139 AF294791 AAM82347 AK001828 AK021757 BAG51044 AK023592 AK098331 BAC05286 AK124569 AY550968 AAT52214 BC009650 AAH09650 BC041361 AAH41361 BC114218 AAI14219 BC126225 AAI26226 BC144088 CA412233 CR749425 CAH18263 EU832459 ACE87631 EU832474 ACE87646 EU832541 ACE86943 EU832553 ACE86955 HQ257985 ADR82739 XM_011513672 XP_011511974 XM_011513673 XP_011511975 XM_011513674 XP_011511976 NM_001100399 NP_001093869 NM_001100400 NP_001093870 NM_015200
Function Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. {ECO:0000269|PubMed:15855230, ECO:0000269|PubMed:19907496}.
Subcellular Location Nucleus {ECO:0000269|PubMed:11076961, ECO:0000269|PubMed:15019998}. Note=Associated with chromatin through most of the cell cycle. Dissociates from chromatin in late prophase, reassociates during late telophase. {ECO:0000269|PubMed:11076961, ECO:0000269|PubMed:15019998}.
Tissue Specificity Highest level in colon. Low levels in lung, ovary, breast and kidney. Reduced level in renal tumor tissue. Isoform 2 is expressed in kidney. {ECO:0000269|PubMed:15019998}.

scc-112 CRISPR/Cas9 KO Plasmid (h) - sc-408205 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

scc-112 HDR Plasmid (h) - sc-408205-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

scc-112 Double Nickase Plasmid (h) - sc-408205-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

scc-112 Double Nickase Plasmid (h2) - sc-408205-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

scc-112 CRISPR Activation Plasmid (h) - sc-408205-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

scc-112 CRISPR Activation Plasmid (h2) - sc-408205-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

scc-112 Lentiviral Activation Particles (h) - sc-408205-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

scc-112 Lentiviral Activation Particles (h2) - sc-408205-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

scc-112 siRNA (h) - sc-61497 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

scc-112 shRNA Plasmid (h) - sc-61497-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

scc-112 shRNA (h) Lentiviral Particles - sc-61497-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU046511 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16580 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16580 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11631 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11631

PDS5A siRNA (Human) - CRH8118 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PDS5A (NM_001100399.1) - SHH373064 from Creative biogene

Category siRNA
Species Reactivities Human

Human PDS5A siRNA - orb268620 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PDS5A shRNA Plasmid (Human) - CHH8118 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PDS5A miRNA 3'UTR clone - MiUTR3H-12781 from Creative biogene

Species Reactivities Human
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