Gene Symbol | NKX3-2 |
---|---|
Entrez Gene | 579 |
Alt Symbol | BAPX1, NKX3.2, NKX3B, SMMD |
Species | Human |
Gene Type | protein-coding |
Description | NK3 homeobox 2 |
Other Description | bagpipe homeobox protein homolog 1|homeobox protein NK-3 homolog B|homeobox protein Nkx-3.2 |
Swissprots | Q2M2I7 P78367 |
Accessions | AAB49696 AAB82784 AAC39536 EAW92714 P78367 AF009801 AAB82783 BC111926 AAI11927 BC111966 AAI11967 BC118497 AAI18498 EU446467 ABZ91996 NM_001189 NP_001180 |
Function | Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Expressed at highest levels in cartilage, bone (osteosarcoma) and gut (small intestine and colon), whereas moderate expression is seen in trachea and brain. Expressed in visceral mesoderm and embryonic skeleton. {ECO:0000269|PubMed:20004766}. |
Nkx-3.2 CRISPR/Cas9 KO Plasmid (h) - sc-406906 from Santa Cruz Biotechnology
|
||||||||
Nkx-3.2 HDR Plasmid (h) - sc-406906-HDR from Santa Cruz Biotechnology
|
||||||||
Nkx-3.2 Double Nickase Plasmid (h) - sc-406906-NIC from Santa Cruz Biotechnology
|
||||||||
Nkx-3.2 Double Nickase Plasmid (h2) - sc-406906-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Nkx-3.2 CRISPR Activation Plasmid (h) - sc-406906-ACT from Santa Cruz Biotechnology
|
||||||||
Nkx-3.2 CRISPR Activation Plasmid (h2) - sc-406906-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Nkx-3.2 Lentiviral Activation Particles (h) - sc-406906-LAC from Santa Cruz Biotechnology
|
||||||||
Nkx-3.2 Lentiviral Activation Particles (h2) - sc-406906-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Nkx-3.2 siRNA (h) - sc-38729 from Santa Cruz Biotechnology
|
||||||||
Nkx-3.2 shRNA Plasmid (h) - sc-38729-SH from Santa Cruz Biotechnology
|
||||||||
Nkx-3.2 shRNA (h) Lentiviral Particles - sc-38729-V from Santa Cruz Biotechnology
|
||||||||
NKX3-2 RNAi - H00000579-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU056691 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN15337 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15337 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR08504 from Sigma-Aldrich
|
||||||||
NKX3-2 siRNA (Human) - CRH0397 from Cohesion Biosciences
|
||||||||
Nkx-3.2 CRISPR/Cas9 KO Plasmid (h2) - sc-406906-KO-2 from Santa Cruz Biotechnology
|
||||||||
Nkx-3.2 HDR Plasmid (h2) - sc-406906-HDR-2 from Santa Cruz Biotechnology
|
||||||||
shRNA set against Human BAPX1(NM_001189.3) - SHR012138 from Creative biogene
|
||||||||
Human NKX3-2 siRNA - orb260899 from Biorbyt
|
||||||||
NKX3-2 shRNA Plasmid (Human) - CHH0397 from Cohesion Biosciences
|
||||||||
NKX3-2 miRNA 3'UTR clone - MiUTR1H-00804 from Creative biogene
|