ASXL1

Gene Symbol	ASXL1
Entrez Gene	171023
Alt Symbol	BOPS, MDS
Species	Human
Gene Type	protein-coding
Description	additional sex combs like transcriptional regulator 1
Other Description	additional sex combs like 1|putative Polycomb group protein ASXL1
Swissprots	Q8IYY7 Q8IXJ9 Q9Y2I4 B2RP59 Q9UFP8 Q9H466 Q9NQF8 Q9UFJ0 Q5JWS9
Accessions	EAW76377 EAW76378 EAW76379 EAW76380 Q8IXJ9 AB023195 BAA76822 AB084280 BAD00087 AJ438952 CAD27708 AK025756 AK122923 BAG53800 AL117518 CAB55975 AL117647 CAB56029 BC033284 AAH33284 BC064984 AAH64984 BC100280 AAI00281 BC137278 AAI37279 BC137280 AAI37281 BQ064719 BU686340 BX109122 CR977683 XM_006723727 XP_006723790 XM_006723728 XP_006723791 XM_006723730 XP_006723793 XM_006723732 XP_006723795 XM_006723733 XP_006723796 XM_011528647 XP_011526949 XM_011528648 XP_011526950 XM_011528649 XP_011526951 XM_011528650 XP_011526952 XM_011528651 XP_011526953 XM_011528652 XP_011526954 NM_001164603 NP_001158075 NM_015338 NP_056153
Function	Probable Polycomb group (PcG) protein involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator of RARA and RXRA through association with NCOA1. Acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters. Acts as corepressor for PPARG and suppresses its adipocyte differentiation-inducing activity (By similarity). Non-catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1). {ECO:0000250, ECO:0000269|PubMed:16606617, ECO:0000269|PubMed:20436459}.
Subcellular Location	Nucleus {ECO:0000250}.
Tissue Specificity	Widely expressed at low level. Expressed in heart, brain, skeletal muscle, placenta, pancreas, spleen, prostate, small intestine, colon, peripheral blood, leukocytes, bone marrow and fetal liver. Highly expressed in testes. {ECO:0000269|PubMed:10231032, ECO:0000269|PubMed:12657473}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ASXL1 (N-13) - sc-85283 from Santa Cruz Biotechnology Prices $279.00 Sizes 100 µg/ml Host Rabbit Clonality Polyclonal

ASXL1 (H-105) - sc-98302 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

ASXL1 (G-20) - sc-85282 from Santa Cruz Biotechnology Prices $279.00 Sizes 100 µg/ml Host Rabbit Clonality Polyclonal

Anti-ASXL1 antibody - ab55825 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ASXL1 antibody [2049C2a] - ab50817 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone 2049C2a

Anti-ASXL1 antibody - N-terminal - ab199861 from Abcam Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ASXL1 Antibody - LS-C63658 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Mouse Clonality Monoclonal

Anti-ASXL1 Antibody (C-Terminus) - LS-C47121 from LifeSpan Bioscience Prices $295.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ASXL1 Antibody (aa528-556, AP) - LS-C232914 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ASXL1 Antibody (aa528-556, Biotin) - LS-C232915 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ASXL1 Antibody (aa528-556, APC) - LS-C232916 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ASXL1 Antibody (aa528-556, Azide-free, HRP) - LS-C249474 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ASXL1 Antibody (aa528-556) - LS-C319646 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ASXL1 Antibody (aa528-556, PE) - LS-C232919 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ASXL1 Antibody (clone 2049C2a) - LS-C184347 from LifeSpan Bioscience Prices $335.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone 2049C2a

Anti-ASXL1 Antibody (aa528-556, FITC) - LS-C232917 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ASXL1 Antibody (clone 2049C2a) - LS-C342399 from LifeSpan Bioscience Prices $375.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2049C2a

Anti-ASXL1 Antibody (clone 6E2) - LS-C139043 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 6E2

Anti-ASXL1 Antibody (aa528-556) - LS-C156556 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

ASXL1 Antibody (6E2) - H00171023-M05 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 6E2

ANTI-ASXL1 (CENTER) antibody produced in rabbit - SAB1302818 from Sigma-Aldrich Prices $326.50 Sizes 100 µg Host Rabbit Clonality Polyclonal

Monoclonal Anti-ASXL1 antibody produced in mouse - SAB1403479 from Sigma-Aldrich Prices $347.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 6E2

ASXL1-Antibody-Center - AP11132c from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

ASXL1 antibody - GTX127284 from GeneTex Prices $119.00 Sizes 25 μl Host Rabbit Clonality Polyclonal

ASXL1 Antibody - middle region (OAAB07377) - OAAB07377 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

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