Gene Symbol | OTX2 |
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Entrez Gene | 5015 |
Alt Symbol | CPHD6, MCOPS5 |
Species | Human |
Gene Type | protein-coding |
Description | orthodenticle homeobox 2 |
Other Description | homeobox protein OTX2|orthodenticle homolog 2 |
Swissprots | B2RAN5 Q9HAW3 P32243 Q9P2R1 Q6GTV3 |
Accessions | AAG16243 AIZ97494 AIZ97495 BAA90425 EAW80692 EAW80693 P32243 AB593056 BAJ84003 AB593057 BAJ84004 AB593058 BAJ84005 AF093138 AAD31385 AK314271 BAG36932 BC032579 AAH32579 BE781530 BU176852 CV812961 DB294481 DQ890875 ABM81801 EU176492 ABW03293 NM_001270523 NP_001257452 NM_001270524 NP_001257453 NM_001270525 NP_001257454 NM_021728 NP_068374 NM_172337 NP_758840 NR_073034 NR_073036 |
Function | Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Expressed in brain. |
OTX2 CRISPR/Cas9 KO Plasmid (h) - sc-416998 from Santa Cruz Biotechnology
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OTX2 HDR Plasmid (h) - sc-416998-HDR from Santa Cruz Biotechnology
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OTX2 Double Nickase Plasmid (h) - sc-416998-NIC from Santa Cruz Biotechnology
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OTX2 Double Nickase Plasmid (h2) - sc-416998-NIC-2 from Santa Cruz Biotechnology
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OTX2 CRISPR Activation Plasmid (h) - sc-416998-ACT from Santa Cruz Biotechnology
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OTX2 CRISPR Activation Plasmid (h2) - sc-416998-ACT-2 from Santa Cruz Biotechnology
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OTX2 Lentiviral Activation Particles (h) - sc-416998-LAC from Santa Cruz Biotechnology
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OTX2 Lentiviral Activation Particles (h2) - sc-416998-LAC-2 from Santa Cruz Biotechnology
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OTX2 siRNA (h) - sc-38741 from Santa Cruz Biotechnology
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OTX2 shRNA Plasmid (h) - sc-38741-SH from Santa Cruz Biotechnology
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OTX2 shRNA (h) Lentiviral Particles - sc-38741-V from Santa Cruz Biotechnology
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Otx2 RNAi - H00005015-R02 from Novus Biologicals
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MISSION® esiRNA - EHU129881 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16205 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16205 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07924 from Sigma-Aldrich
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OTX2 siRNA (Human) - CRH3329 from Cohesion Biosciences
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Otx2 RNAi - H00005015-R01 from Novus Biologicals
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shRNA set against Human OTX2 (NM_021728.3) - SHH369204 from Creative biogene
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Human OTX2 siRNA - orb263831 from Biorbyt
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OTX2 shRNA Plasmid (Human) - CHH3329 from Cohesion Biosciences
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OTX2 miRNA 3'UTR clone - MiUTR3H-03090 from Creative biogene
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OTX2 miRNA 3'UTR clone - MiUTR3H-03091 from Creative biogene
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