Gene Symbol | AK6 |
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Entrez Gene | 102157402 |
Alt Symbol | AD-004, CGI-137, CINAP, CIP, hCINAP |
Species | Human |
Gene Type | protein-coding |
Description | adenylate kinase 6 |
Other Description | ATP-AMP transphosphorylase 6|adenylate kinase isoenzyme 6|adrenal gland protein AD-004|coilin interacting nuclear ATPase protein|coilin interacting protein |
Swissprots | Q5F2S9 A8MSZ6 Q9Y3D8 |
Accessions | Q9Y3D8 AF110777 AAF14860 AF151895 AAD34132 AJ878880 CAI48030 AJ878881 CAI48031 BC007426 AAH07426 BX117839 NM_001015891 NP_001015891 NM_016283 NP_057367 |
Function | Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. AMP and dAMP are the preferred substrates, but CMP and dCMP are also good substrates. IMP is phosphorylated to a much lesser extent. All nucleoside triphosphates ATP, GTP, UTP, CTP, dATP, dCTP, dGTP, and TTP are accepted as phosphate donors. CTP is the best phosphate donor, followed by UTP, ATP, GTP and dCTP. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation. {ECO:0000269|PubMed:15630091}. |
Subcellular Location | Nucleus, nucleoplasm. Nucleus, Cajal body. Note=Displays widespread diffuse nucleoplasmic distribution but not detected in nucleoli. Detected in Cajal bodies but not in all cells. |
Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, chorionic villi and the central nervous system. {ECO:0000269|PubMed:16079131}. |
Top Pathways | Ribosome biogenesis in eukaryotes, Purine metabolism |
Anti-AK6 / Adenylate Kinase 6 Antibody (Gly35) - LS-C191992 from LifeSpan Bioscience
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Anti-AK6 / Adenylate Kinase 6 Antibody (aa11-60) - LS-C119343 from LifeSpan Bioscience
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CINAP Antibody - NBP1-91787 from Novus Biologicals
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TAF9 Antibody - NBP1-55763 from Novus Biologicals
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CINAP Antibody - NB100-93566 from Novus Biologicals
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Anti -AK6 (Adenylate Kinase isoenzyme 6, AK6, Adrenal gland Protein AD-004,Coilin-interacting Nuclear ATPase Protein, hCINAP, Dual activity adenylate Kinase/ATPase,AK/ATPase, CINAP, AD-004, CGI-137) - 220642 from USBiological Life Science
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Anti -AK6 (Adenylate Kinase isoenzyme 6, AK6, Adrenal gland Protein AD-004,Coilin-interacting Nuclear ATPase Protein, hCINAP, Dual activity adenylate Kinase/ATPase,AK/ATPase, CINAP, AD-004, CGI-137) - 220643 from USBiological Life Science
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AK3 antibody - 10R-3236 from Fitzgerald
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AK3 antibody - 10R-3233 from Fitzgerald
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AK3 antibody - 10R-3231 from Fitzgerald
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AK3 antibody - 10R-3237 from Fitzgerald
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AK3 antibody - 10R-3235 from Fitzgerald
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AK3 antibody - 10R-1020 from Fitzgerald
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AK3 antibody - 10R-3232 from Fitzgerald
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KAD6 Antibody - abx119084 from Abbexa
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Anti-AK3, Polyclonal Antibody - 25-A4694 from ARP American Research Products
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Anti-AK6 (G35) - 31-B2171 from ARP American Research Products
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TAF9 Antibody - 28-123 from ProSci
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KAD6 Polyclonal Antibody - PA002106-C11948 from Syd Labs
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KAD6 Antibody - E11-11948C from Enogene
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TAF9 Antibody - GWB-92B4DB from Genway Biotech
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AK5 Polyclonal Antibody - ESAP13286 from Elabscience
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AK5 Antibody - EPP10275 from Elabscience
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AK3 antibody (clone SJB3-36) - ABC-142 from Reagent Proteins
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AK6 (G35) polyclonal antibody - BS2171 from Bioworld Technology
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