Gene Symbol | AK6 |
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Entrez Gene | 102157402 |
Alt Symbol | AD-004, CGI-137, CINAP, CIP, hCINAP |
Species | Human |
Gene Type | protein-coding |
Description | adenylate kinase 6 |
Other Description | ATP-AMP transphosphorylase 6|adenylate kinase isoenzyme 6|adrenal gland protein AD-004|coilin interacting nuclear ATPase protein|coilin interacting protein |
Swissprots | Q5F2S9 A8MSZ6 Q9Y3D8 |
Accessions | Q9Y3D8 AF110777 AAF14860 AF151895 AAD34132 AJ878880 CAI48030 AJ878881 CAI48031 BC007426 AAH07426 BX117839 NM_001015891 NP_001015891 NM_016283 NP_057367 |
Function | Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. AMP and dAMP are the preferred substrates, but CMP and dCMP are also good substrates. IMP is phosphorylated to a much lesser extent. All nucleoside triphosphates ATP, GTP, UTP, CTP, dATP, dCTP, dGTP, and TTP are accepted as phosphate donors. CTP is the best phosphate donor, followed by UTP, ATP, GTP and dCTP. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation. {ECO:0000269|PubMed:15630091}. |
Subcellular Location | Nucleus, nucleoplasm. Nucleus, Cajal body. Note=Displays widespread diffuse nucleoplasmic distribution but not detected in nucleoli. Detected in Cajal bodies but not in all cells. |
Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, chorionic villi and the central nervous system. {ECO:0000269|PubMed:16079131}. |
Top Pathways | Ribosome biogenesis in eukaryotes, Purine metabolism |
Human AK6 full length protein - ab104633 from Abcam
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TAF9 / AK6 (1-172, His-tag) - AR09838PU-L from Acris Antibodies
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TAF9 / AK6 (1-172, His-tag) - AR09838PU-N from Acris Antibodies
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TAF9 / AK6 - H00006880-P01 from Acris Antibodies
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TAF9 / AK6 - H00006880-Q01-10 from Acris Antibodies
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TAF9 / AK6 - H00006880-Q01-25 from Acris Antibodies
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TAF9, 1-172aa, Human, His tag, E.coli - 01-P0898 from ARP American Research Products
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TAF9 fusion protein - Ag0833 from Proteintech Group
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TAF9, 1-172aa, Recombinant Protein - GWB-P1140I from Genway Biotech
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TAF9 1-172aa - CMB-731 from Reagent Proteins
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AK6 (G35) Peptide - BS2171P from Bioworld Technology
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Recombinant Alkaline Phosphatase, Intestinal (ALPI) - RPB085Hu01 from Cloud-clone
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Recombinant Human Adenylate kinase isoenzyme 6(TAF9) - CSB-YP897106HU CSB-EP897106HU CSB-BP897106HU CSB-MP897106HU from Cusabio
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TAF9, 1-172aa, Human, His tag, E.coli - ATGP0898 from ATGen
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Adenylate kinase isoenzyme 6 (TAF9) - MBS1441305 from MyBioSource
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TAF9 / AK6 (transcript variant 2) - TP300412 from Acris Antibodies
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TAF9, Recombinant Protein - MBS203894 from MyBioSource
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Adenylate Kinase 6 Blocking Peptide - abx061250 from Abbexa
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Adenylate Kinase 6 Blocking Peptide - CBP5163 from Cohesion Biosciences
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TAF9 - PAT-80938-1 from Nordic BioSite
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TAF9 - PAT-80938-2 from Nordic BioSite
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Adenylate Kinase 6 Recombinant Protein Antigen - NBP2-56093PEP from Novus Biologicals
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AK6 peptide - orb319309 from Biorbyt
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