TRIM68

Gene Symbol TRIM68
Entrez Gene 55128
Alt Symbol GC109, RNF137, SS-56, SS56
Species Human
Gene Type protein-coding
Description tripartite motif containing 68
Other Description E3 ubiquitin-protein ligase TRIM68|Ro/SSA1 related protein|SSA protein SS-56|ring finger protein 137|tripartite motif-containing protein 68
Swissprots Q8WZ70 Q9H9C2 Q6AZZ1 Q96PF7 Q9NW18 A6NI19 B4DVK4 A8K551 B3KPM5 Q96LE5
Accessions CAK32341 EAW68834 EAW68835 Q6AZZ1 AF360739 AAL11501 AF439153 AAL31641 AK001231 BAA91569 AK022923 BAB14309 AK056523 BAG51737 AK291166 BAF83855 AK301120 BAG62716 AK310888 AL832730 AM392750 CAL37628 AY005802 AAF91075 BC075058 AAH75058 BC109063 AAI09064 DA833140 DC402744 EU446815 ABZ92344 NM_001304496 NP_001291425 NM_018073 NP_060543
Function Functions as a ubiquitin E3 ligase. Acts as a coactivator of androgen receptor (AR) depending on its ubiquitin ligase activity. {ECO:0000269|PubMed:18451177}.
Subcellular Location Cytoplasm, perinuclear region. Nucleus. Note=Colocalized with AR in nucleus.
Tissue Specificity Widely expressed. Expressed at high levels in prostate cancer cell lines. Up-regulation could be restricted to androgen-dependent cells. {ECO:0000269|PubMed:11560955, ECO:0000269|PubMed:11597395, ECO:0000269|PubMed:18451177}.

TRIM68 (L-14) - sc-169683 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TRIM68 (N-15) - sc-169684 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TRIM68 (P-20) - sc-130049 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
TRIM68 (P-20): sc-130049. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney showing cytoplasmic staining.

Anti-TRIM68 antibody - ab86393 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-TRIM68 antibody (ab86393) at 1 µg/ml + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-TRIM68 antibody - ab57436 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57436 TRIM68 antibody at 1ug/ml.

Anti-TRIM68 antibody - C-terminal - ab172918 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-TRIM68 antibody - C-terminal (ab172918) at 1/100 dilution + NCI-H460 cell line lysate at 35 µg

Anti-TRIM68 Antibody (aa381-411, AP) - LS-C272252 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIM68 Antibody (aa381-411, APC) - LS-C272253 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIM68 Antibody (aa381-411, Biotin) - LS-C272254 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIM68 Antibody (aa381-411, FITC) - LS-C272255 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIM68 Antibody (aa381-411, Azide-free, HRP) - LS-C272256 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIM68 Antibody (aa381-411, PE) - LS-C272257 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIM68 Antibody (aa397-446) - LS-C31161 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Jurkat Cell Lysate

Anti-TRIM68 Antibody (aa381-411) - LS-C325965 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIM68 Antibody (aa382-411) - LS-C157280 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
TRIM68 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The TRIM68 antibody detected the TRIM68 protein (arrow).

Anti-TRIM68 Antibody (aa279-328) IHC-plus™ - LS-B1110 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TRIM68 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1110 concentration 5 ug/ml.

Anti-TRIM68 Antibody (aa395-444) IHC-plus™ - LS-B3531 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TRIM68 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3531 concentration 5 ug/ml.

TRIM68 Antibody - NBP1-83863 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: TRIM68 Antibody [NBP1-83863] - Staining of human cell line U-2 OS shows positivity in nucleus, nucleoli & cytoplasm.

TRIM68 Antibody - NBP2-20724 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TRIM68 Antibody (5G2) - H00055128-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5G2
Sandwich ELISA: TRIM68 Antibody (5G2) [H00055128-M01] - Detection limit for recombinant GST tagged TRIM68 is approximately 0.3ng/ml as a capture antibody.

TRIM68 Antibody - H00055128-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-TRIM68 (AB2) antibody produced in rabbit - AV34460 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TRIM68 (ab2): <B>Cat. No. AV34460</B>: Immunohistochemistry of TRIM68 in Human Muscle tissue with TRIM68 antibody at 4-8 μg/mL.

Monoclonal Anti-TRIM68 antibody produced in mouse - WH0055128M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5G2
<B>Immunoblotting</B><BR/>Monoclonal Anti-TRIM68, <B>Cat. No. WH0055128M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~37.11 kDa using immunogen protein lysate.

Anti-TRIM68 (321-335) antibody produced in rabbit - T3204 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-TRIM68 (321-335): <B>Cat. No. T3204</B>: Immunofluorescence of HUVEC cells using TRIM68 (321-335) (RB),<B>Cat. No. T3204</B> (red) at a 1:100 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-TRIM68 antibody produced in rabbit - HPA023455 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TRIM68: <B>Cat. No. HPA023455</B>: Immunohistochemical staining of human duodenum shows strong cytoplasmic and membranous positivity in glandular cells.
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