| Gene Symbol |
FCRL4
|
| Entrez Gene |
83417
|
| Alt Symbol |
CD307d, FCRH4, IGFP2, IRTA1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Fc receptor-like 4
|
| Other Description |
Fc receptor-like protein 4|IFGP family protein 2|fc receptor homolog 4|fcR-like protein 4|hIFGP2|immune receptor translocation-associated protein 1|immunoglobulin superfamily Fc receptor, gp42|immunoglobulin superfamily receptor translocation associated 1
|
| Swissprots |
Q96RE0 Q96PJ3 Q96PJ5
|
| Accessions |
ABK41914 EAW52882 EAW52883 Q96PJ5 AF329490 AAL23900 AF329492 AAL23902 AF343659 AAK31322 AF343660 AAK31323 AF343661 AAK31324 AF397452 AAK93970 BC125173 AAI25174 BC125174 AAI25175 BC143628 XM_011510034 XP_011508336 NM_031282 NP_112572
|
| Function |
May function as an inhibitor of the B-cell receptor signaling. May function in the B-cell-mediated immune response. {ECO:0000269|PubMed:14597715}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:16157685, ECO:0000269|PubMed:16849395}; Single-pass type I membrane protein {ECO:0000269|PubMed:16157685, ECO:0000269|PubMed:16849395}.
|
| Tissue Specificity |
Specifically expressed by memory and monocytoid B-cells which populate spleen and lymph nodes. Preferentially expressed in memory B-cells associated with mucosal tissue (at protein level). {ECO:0000269|PubMed:11290337, ECO:0000269|PubMed:11929751, ECO:0000269|PubMed:12881317, ECO:0000269|PubMed:16079106, ECO:0000269|PubMed:16157685, ECO:0000269|PubMed:16849395}.
|