Gene Symbol | FCRL4 |
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Entrez Gene | 83417 |
Alt Symbol | CD307d, FCRH4, IGFP2, IRTA1 |
Species | Human |
Gene Type | protein-coding |
Description | Fc receptor-like 4 |
Other Description | Fc receptor-like protein 4|IFGP family protein 2|fc receptor homolog 4|fcR-like protein 4|hIFGP2|immune receptor translocation-associated protein 1|immunoglobulin superfamily Fc receptor, gp42|immunoglobulin superfamily receptor translocation associated 1 |
Swissprots | Q96RE0 Q96PJ3 Q96PJ5 |
Accessions | ABK41914 EAW52882 EAW52883 Q96PJ5 AF329490 AAL23900 AF329492 AAL23902 AF343659 AAK31322 AF343660 AAK31323 AF343661 AAK31324 AF397452 AAK93970 BC125173 AAI25174 BC125174 AAI25175 BC143628 XM_011510034 XP_011508336 NM_031282 NP_112572 |
Function | May function as an inhibitor of the B-cell receptor signaling. May function in the B-cell-mediated immune response. {ECO:0000269|PubMed:14597715}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:16157685, ECO:0000269|PubMed:16849395}; Single-pass type I membrane protein {ECO:0000269|PubMed:16157685, ECO:0000269|PubMed:16849395}. |
Tissue Specificity | Specifically expressed by memory and monocytoid B-cells which populate spleen and lymph nodes. Preferentially expressed in memory B-cells associated with mucosal tissue (at protein level). {ECO:0000269|PubMed:11290337, ECO:0000269|PubMed:11929751, ECO:0000269|PubMed:12881317, ECO:0000269|PubMed:16079106, ECO:0000269|PubMed:16157685, ECO:0000269|PubMed:16849395}. |
FcRH4 CRISPR/Cas9 KO Plasmid (h) - sc-413462 from Santa Cruz Biotechnology
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FcRH4 HDR Plasmid (h) - sc-413462-HDR from Santa Cruz Biotechnology
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FcRH4 Double Nickase Plasmid (h) - sc-413462-NIC from Santa Cruz Biotechnology
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FcRH4 Double Nickase Plasmid (h2) - sc-413462-NIC-2 from Santa Cruz Biotechnology
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FcRH4 CRISPR Activation Plasmid (h) - sc-413462-ACT from Santa Cruz Biotechnology
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FcRH4 CRISPR Activation Plasmid (h2) - sc-413462-ACT-2 from Santa Cruz Biotechnology
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FcRH4 Lentiviral Activation Particles (h) - sc-413462-LAC from Santa Cruz Biotechnology
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FcRH4 Lentiviral Activation Particles (h2) - sc-413462-LAC-2 from Santa Cruz Biotechnology
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FcRH4 siRNA (h) - sc-60629 from Santa Cruz Biotechnology
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FcRH4 shRNA Plasmid (h) - sc-60629-SH from Santa Cruz Biotechnology
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FcRH4 shRNA (h) Lentiviral Particles - sc-60629-V from Santa Cruz Biotechnology
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FCRL4/FcRH4/IRTA1 RNAi - H00083417-R02 from Novus Biologicals
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MISSION® esiRNA - EHU129301 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8604 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8604 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10482 from Sigma-Aldrich
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FCRL4 siRNA (Human) - CRJ3093 from Cohesion Biosciences
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FCRL4 - MBS828888 from MyBioSource
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shRNA set against Human FCRL4 (NM_031282.2) - SHH293869 from Creative biogene
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Human FCRL4 siRNA - orb273594 from Biorbyt
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FCRL4 shRNA Plasmid (Human) - CHJ3093 from Cohesion Biosciences
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FCRL4 miRNA 3'UTR clone - MiUTR4H-TG03508 from Creative biogene
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