| Gene Symbol |
LIM2
|
| Entrez Gene |
3982
|
| Alt Symbol |
CTRCT19, MP17, MP19
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
lens intrinsic membrane protein 2, 19kDa
|
| Other Description |
MP18|MP20|lens fiber membrane intrinsic protein
|
| Swissprots |
Q9BXD0 Q6B083 Q9HAR5 P55344
|
| Accessions |
AAG32328 EAW72010 EAW72011 P55344 AF340019 AAK26327 AF340020 AAK26328 BC069430 AAH69430 BC074916 AAH74916 BC074917 AAH74917 BC126139 AAI26140 BU734982 CD675859 HQ258752 ADR83503 NM_001161748 NP_001155220 NM_030657 NP_085915
|
| Function |
Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Eye lens specific. {ECO:0000269|PubMed:12107413}.
|