| Gene Symbol |
Cyp24a1
|
| Entrez Gene |
13081
|
| Alt Symbol |
24-OHase, CP24, Cyp24
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450, family 24, subfamily a, polypeptide 1
|
| Other Description |
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial|25-hydroxyvitamin D-24-hydroxylase|cytochrome P450 24A1|cytochrome P450, 24|cytochrome P450, 24a1|cytochrome P450-CC24|vitamin D(3) 24-hydroxylase
|
| Swissprots |
Q64441
|
| Accessions |
EDL06583 Q64441 AK016668 AK143984 BAE25646 AK159109 BAE34825 AK159481 BAE35118 AK159527 BAE35156 AK159852 BAE35429 AK159954 BAE35510 AK159976 BAE35528 AK164697 BAE37882 BC109139 AAI09140 BC109140 AAI09141 D49438 BAA08416 D89669 BAA21843 NM_009996 NP_034126
|
| Function |
Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25- hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid.
|
| Subcellular Location |
Mitochondrion.
|
| Top Pathways |
MicroRNAs in cancer, Steroid biosynthesis
|