| Gene Symbol | VAX2 |
|---|---|
| Entrez Gene | 25806 |
| Alt Symbol | DRES93 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ventral anterior homeobox 2 |
| Other Description | - |
| Swissprots | Q53Y33 Q9UIW0 |
| Accessions | EAW99792 Q9UIW0 AB593145 BAJ84079 BC006336 AAH06336 BT007035 AAP35683 Y17791 CAB56166 XM_006711982 XP_006712045 XM_011532749 XP_011531051 XM_011532750 XP_011531052 XM_011532751 XP_011531053 XM_011532752 XP_011531054 NM_012476 NP_036608 |
| Function | Transcription factor that may function in dorsoventral specification of the forebrain. Regulates the expression of Wnt signaling antagonists including the expression of a truncated TCF7L2 isoform that cannot bind CTNNB1 and acts therefore as a potent dominant-negative Wnt antagonist. Plays a crucial role in eye development and, in particular, in the specification of the ventral optic vesicle (By similarity). May be a regulator of axial polarization in the retina. {ECO:0000250}. |
| Subcellular Location | Nucleus {ECO:0000305}. |
ventral anterior homeobox 2, ELISA Kit - MBS9320105 from MyBioSource
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Human VAX2 ELISA Kit - E102478 from Biobool
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