EPHX2

Gene Symbol	EPHX2
Entrez Gene	2053
Alt Symbol	CEH, SEH
Species	Human
Gene Type	protein-coding
Description	epoxide hydrolase 2, cytoplasmic
Other Description	bifunctional epoxide hydrolase 2|epoxide hydratase|epoxide hydrolase 2, cytosolic|epoxide hydrolase, soluble
Swissprots	J3KPH7 Q9HBJ2 Q9HBJ1 P34913 G3V134 Q16764 B3KUA0 B3KTU8 B2Z3B1
Accessions	ACD11487 CAA65751 EAW63547 EAW63548 EAW63549 EAW63550 EAW63551 P34913 AF233334 AAG14966 AF233335 AAG14967 AF233336 AAG14968 AK094393 AK096089 BAG53210 AK096770 BAG53362 AK294065 BAG57410 AK303904 BAG64834 AK308041 AK310507 BC007708 AAH07708 BC011628 AAH11628 BC013874 AAH13874 BQ272362 BT006885 AAP35531 BX103698 CA397329 DC331720 DQ892749 ABM83675 DQ895995 ABM86963 L05779 AAA02756 NM_001256482 NP_001243411 NM_001256483 NP_001243412 NM_001256484 NP_001243413 NM_001979 NP_001970
Function	Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators. The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo- 9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro- 9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy- octadec-9Z-enoic acid, 12-phosphonooxy-octadec-9E-enoic acid, and p-nitrophenyl phospate. {ECO:0000269|PubMed:12574508, ECO:0000269|PubMed:12574510}.
Subcellular Location	Cytoplasm. Peroxisome.
Top Pathways	Peroxisome, Arachidonic acid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human EPHX2 full length protein - ab158378 from Abcam Category Protein Source Wheat germ Species Human

Human EPHX2 protein fragment - ab158379 from Abcam Category Protein Source Wheat germ Species Human

EPHX2 / Epoxide Hydrolase 2 Antibody Blocking Peptide - LS-E29531 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

EPHX2 / Epoxide Hydrolase 2 Antibody Blocking Peptide - LS-E29532 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

EPHX2 / Epoxide Hydrolase 2 Antibody Blocking Peptide - LS-E29534 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human EPHX2 Protein - H00002053-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human EPHX2 Protein - H00002053-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Human EPHX2 (His Tag) protein - orb232343 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Species Human

E.coli SEH protein - orb246520 from Biorbyt Category Protein Prices $213.00, $408.00, $680.00, $1,122.00, $1,777.00 Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg Species Escherichia coli

Human EPHX2 protein - orb246337 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Epoxide hydrolase 2 / EPHX2 - H00002053-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Epoxide hydrolase 2 / EPHX2 - H00002053-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Epoxide hydrolase 2 / EPHX2 - H00002053-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Epoxide hydrolase 2 / EPHX2 - H00002053-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

EPHX2 fusion protein - Ag4870 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

EPHX2 fusion protein - Ag1283 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Human EPHX2 / SHE Protein (His Tag) - 14856-H07B-20 from Sino Biological Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Human Epoxide hydrolase 2(EPHX2) - CSB-YP007735HU CSB-BP007735HU CSB-MP007735HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant Human Epoxide hydrolase 2(EPHX2) - CSB-EP007735HU from Cusabio Category Protein Species Human

Epoxide hydrolase 2 / EPHX2 - TP302489 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human EPHX2 Protein, His-tagged - EPHX2-638H from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Human

EPHX2 Recombinant Protein Antigen - NBP1-89534PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

EPHX2 Recombinant Protein Antigen - NBP1-89531PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

EPHX2 Protein - NBP1-89529PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

EPHX2 Peptide, Human - M34GP04998H from Creative Peptides Category Peptide Source Synthetic. Species Human

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