Gene Symbol |
NAPRT
|
Entrez Gene |
93100
|
Alt Symbol |
NAPRT1, PP3856
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
nicotinate phosphoribosyltransferase
|
Other Description |
FHA-HIT-interacting protein|NAPRTase|nicotinate phosphoribosyltransferase domain containing 1|nicotinate phosphoribosyltransferase domain-containing protein 1|nicotinic acid phosphoribosyltransferase
|
Swissprots |
Q9BRG0 Q6XQN4 Q8N5E8 Q6XQN5 Q6PJL1 A7BFI3 Q6XQN6
|
Accessions |
EAW82236 EAW82237 EAW82238 EAW82239 EAW82240 Q6XQN6 AB242230 BAF75377 AF258565 AAG23768 AK097002 AY214325 AAP69603 AY214326 AAP69604 AY214327 AAP69605 BC006284 AAH06284 BC014190 BC032466 AAH32466 CN260784 XM_011517377 XP_011515679 XM_011546547 XP_011544849 NM_001286829 NP_001273758 NM_145201 NP_660202
|
Function |
Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN). Essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. {ECO:0000269|PubMed:17604275}.
|
Subcellular Location |
Cytoplasm, cytosol {ECO:0000269|PubMed:17604275}.
|
Top Pathways |
Nicotinate and nicotinamide metabolism
|