Gene Symbol | NAPRT |
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Entrez Gene | 93100 |
Alt Symbol | NAPRT1, PP3856 |
Species | Human |
Gene Type | protein-coding |
Description | nicotinate phosphoribosyltransferase |
Other Description | FHA-HIT-interacting protein|NAPRTase|nicotinate phosphoribosyltransferase domain containing 1|nicotinate phosphoribosyltransferase domain-containing protein 1|nicotinic acid phosphoribosyltransferase |
Swissprots | Q9BRG0 Q6XQN4 Q8N5E8 Q6XQN5 Q6PJL1 A7BFI3 Q6XQN6 |
Accessions | EAW82236 EAW82237 EAW82238 EAW82239 EAW82240 Q6XQN6 AB242230 BAF75377 AF258565 AAG23768 AK097002 AY214325 AAP69603 AY214326 AAP69604 AY214327 AAP69605 BC006284 AAH06284 BC014190 BC032466 AAH32466 CN260784 XM_011517377 XP_011515679 XM_011546547 XP_011544849 NM_001286829 NP_001273758 NM_145201 NP_660202 |
Function | Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN). Essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. {ECO:0000269|PubMed:17604275}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:17604275}. |
Top Pathways | Nicotinate and nicotinamide metabolism |
NAPRT CRISPR/Cas9 KO Plasmid (h) - sc-406144 from Santa Cruz Biotechnology
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NAPRT HDR Plasmid (h) - sc-406144-HDR from Santa Cruz Biotechnology
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NAPRT Double Nickase Plasmid (h) - sc-406144-NIC from Santa Cruz Biotechnology
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NAPRT Double Nickase Plasmid (h2) - sc-406144-NIC-2 from Santa Cruz Biotechnology
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NAPRT CRISPR Activation Plasmid (h) - sc-406144-ACT from Santa Cruz Biotechnology
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NAPRT CRISPR Activation Plasmid (h2) - sc-406144-ACT-2 from Santa Cruz Biotechnology
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NAPRT Lentiviral Activation Particles (h) - sc-406144-LAC from Santa Cruz Biotechnology
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NAPRT Lentiviral Activation Particles (h2) - sc-406144-LAC-2 from Santa Cruz Biotechnology
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NAPRT siRNA (h) - sc-77596 from Santa Cruz Biotechnology
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NAPRT shRNA Plasmid (h) - sc-77596-SH from Santa Cruz Biotechnology
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NAPRT shRNA (h) Lentiviral Particles - sc-77596-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU086131 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14955 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14955 from Sigma-Aldrich
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NAPRT1 siRNA (Human) - CRJ4188 from Cohesion Biosciences
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shRNA set against Human NAPRT1 (NM_145201.4) - SHH349336 from Creative biogene
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NAPRT1 shRNA Plasmid (Human) - CHJ4188 from Cohesion Biosciences
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NAPRT1 miRNA 3'UTR clone - MiUTR3H-11972 from Creative biogene
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