Gene Symbol | ATP6V0D1 |
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Entrez Gene | 9114 |
Alt Symbol | ATP6D, ATP6DV, P39, VATX, VMA6, VPATPD |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 |
Other Description | 32 kDa accessory protein|ATPase, H+ transporting, lysosomal (vacuolar proton pump), member D|H(+)-transporting two-sector ATPase, subunit D|V-ATPase 40 KDa accessory protein|V-ATPase AC39 subunit|V-ATPase subunit d 1|V-ATPase, subunit D|V-type proton ATPase subunit d 1|vacuolar proton pump subunit d 1 |
Swissprots | Q02547 P12953 P61421 |
Accessions | EAW83135 EAW83136 P61421 AK125522 AK128641 AK300570 BAH13305 AK301630 BAH13524 AK313035 BAG35868 BC008861 AAH08861 BI552108 BM677562 DQ893270 ABM84196 DQ896601 ABM87600 L05087 AAC15852 X71490 CAA50591 XM_011523444 XP_011521746 XM_011523445 XP_011521747 XM_011523446 XP_011521748 XM_011523447 XP_011521749 NM_004691 NP_004682 |
Function | Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305|PubMed:21844891}; Peripheral membrane protein {ECO:0000305|PubMed:21844891}; Cytoplasmic side {ECO:0000305|PubMed:21844891}. Note=Localizes to centrosome and the base of the cilium. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:12384298, ECO:0000269|PubMed:8250920}. |
Top Pathways | Lysosome, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis, Synaptic vesicle cycle |
V-ATPase D1 (C-16) - sc-69105 from Santa Cruz Biotechnology
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V-ATPase D1 (H-40) - sc-366079 from Santa Cruz Biotechnology
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V-ATPase D1 (D-4) - sc-393322 from Santa Cruz Biotechnology
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V-ATPase D1 (N-16) - sc-69106 from Santa Cruz Biotechnology
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V-ATPase D1 (34-Z) - sc-81887 from Santa Cruz Biotechnology
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Anti-ATP6V0D1 antibody - ab56441 from Abcam
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Anti-ATP6V0D1 antibody - ab191908 from Abcam
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Anti-ATP6V0D1 antibody - ab134985 from Abcam
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Anti-ATP6V0D1 Antibody (aa280-325) - LS-C313993 from LifeSpan Bioscience
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Anti-ATP6V0D1 Antibody (aa275-324) - LS-C152191 from LifeSpan Bioscience
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Anti-ATP6V0D1 Antibody - LS-C341055 from LifeSpan Bioscience
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Anti-ATP6V0D1 Antibody (aa201-250) - LS-C152192 from LifeSpan Bioscience
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Anti-ATP6V0D1 Antibody (aa221-270) - LS-C200048 from LifeSpan Bioscience
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Anti-ATP6V0D1 Antibody (clone 2G12) - LS-C104911 from LifeSpan Bioscience
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ATP6V0D1 Antibody (2G12) - H00009114-M01 from Novus Biologicals
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ATP6V0D1 Antibody - NBP1-88893 from Novus Biologicals
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ATP6V0D1 Antibody - NBP2-15517 from Novus Biologicals
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ATP6V0D1 Antibody (3B7) - H00009114-M19 from Novus Biologicals
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ATP6V0D1 Antibody - H00009114-A01 from Novus Biologicals
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Monoclonal Anti-ATP6V0D1 antibody produced in mouse - WH0009114M1 from Sigma-Aldrich
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Monoclonal Anti-ATP6V0D1 antibody produced in mouse - SAB1404674 from Sigma-Aldrich
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Anti-ATP6V0D1 antibody produced in rabbit - HPA016938 from Sigma-Aldrich
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ATP6V0D1 Antibody - C-terminal region (ARP66521_P050) - ARP66521_P050 from Aviva Systems Biology
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ATP6V0D1 Antibody - C-terminal region (ARP66522_P050) - ARP66522_P050 from Aviva Systems Biology
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ATP6V0D1-Antibody-monoclonal-M01 - AT1240a from Abgent, a WuXi AppTec company
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