| Gene Symbol | ATP6V0D1 |
|---|---|
| Entrez Gene | 9114 |
| Alt Symbol | ATP6D, ATP6DV, P39, VATX, VMA6, VPATPD |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 |
| Other Description | 32 kDa accessory protein|ATPase, H+ transporting, lysosomal (vacuolar proton pump), member D|H(+)-transporting two-sector ATPase, subunit D|V-ATPase 40 KDa accessory protein|V-ATPase AC39 subunit|V-ATPase subunit d 1|V-ATPase, subunit D|V-type proton ATPase subunit d 1|vacuolar proton pump subunit d 1 |
| Swissprots | Q02547 P12953 P61421 |
| Accessions | EAW83135 EAW83136 P61421 AK125522 AK128641 AK300570 BAH13305 AK301630 BAH13524 AK313035 BAG35868 BC008861 AAH08861 BI552108 BM677562 DQ893270 ABM84196 DQ896601 ABM87600 L05087 AAC15852 X71490 CAA50591 XM_011523444 XP_011521746 XM_011523445 XP_011521747 XM_011523446 XP_011521748 XM_011523447 XP_011521749 NM_004691 NP_004682 |
| Function | Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). {ECO:0000250}. |
| Subcellular Location | Membrane {ECO:0000305|PubMed:21844891}; Peripheral membrane protein {ECO:0000305|PubMed:21844891}; Cytoplasmic side {ECO:0000305|PubMed:21844891}. Note=Localizes to centrosome and the base of the cilium. |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:12384298, ECO:0000269|PubMed:8250920}. |
| Top Pathways | Lysosome, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis, Synaptic vesicle cycle |