| Gene Symbol |
IFNK
|
| Entrez Gene |
56832
|
| Alt Symbol |
IFNT1, INFE1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
interferon, kappa
|
| Other Description |
IFN-kappa|interferon kappa|interferon-like protein
|
| Swissprots |
Q9P0W0 Q5T166
|
| Accessions |
AAK63835 EAW58563 Q9P0W0 AF146759 AAF67468 AF315688 AAK01623 AY358855 AAQ89214 BC140280 AAI40281 BC141647 AAI41648 NM_020124 NP_064509
|
| Function |
May play a role in the regulation of immune cell function. Cytokine that imparts cellular protection against viral infection in a species-specific manner. Activates the interferon- stimulated response element signaling pathway. It is able to directly modulate cytokine release from monocytes and dendritic cells. Binds heparin. {ECO:0000269|PubMed:11514542, ECO:0000269|PubMed:12391192}.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Expressed in keratinocytes, monocytes and in resting dendritic cells. {ECO:0000269|PubMed:11514542, ECO:0000269|PubMed:12391192}.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, RIG-I-like receptor signaling pathway
|
