Gene Symbol |
NUDT12
|
Entrez Gene |
83594
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
nudix (nucleoside diphosphate linked moiety X)-type motif 12
|
Other Description |
nucleoside diphosphate linked moiety X-type motif 12|nucleoside diphosphate-linked moiety X motif 12|nudix motif 12|peroxisomal NADH pyrophosphatase NUDT12
|
Swissprots |
Q8TAL7 B3KUW2 Q9BQG2
|
Accessions |
EAW49073 Q9BQG2 AK098066 BAG53574 AK304010 BAG64925 AK309942 AL136592 CAB66527 AM392531 CAL37409 BC026748 AAH26748 BC041099 AAH41099 BC042967 BU621954 CB131118 DB029218 DC417976 XM_005272095 XP_005272152 XM_005272097 XP_005272154 NM_001300741 NP_001287670 NM_031438 NP_113626
|
Function |
Hydrolyzes NAD(P)H to NMNH and AMP (2',5'-ADP), and diadenosine diphosphate to AMP. Has also activity towards NAD(P)(+), ADP-ribose and diadenosine triphosphate. May act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism in this organelle. {ECO:0000269|PubMed:12790796}.
|
Subcellular Location |
Peroxisome {ECO:0000269|PubMed:12790796}.
|
Top Pathways |
Peroxisome, Nicotinate and nicotinamide metabolism
|